Table 2.

Comparative study of iron indices parameters of pC282Y homozygous females


Cohort of the pC282Y homozygous females*

The 4 females with a HAMP gene mutation
Age range, y
No. of patients
Means of SF, μg/L
Means of TS, %
HAMP mutation
Age-D, y
SF, μg/L
TS, %
Phlebotomy IR, g
45-55   37   670 ± 1307   75.5 ± 19.4   pR59G   50   719   97   10.2  
55-65   39   719 ± 1070   72.9 ± 15.7   pG71D   61   852   86   6.5  
     pR56X   62   265   97   3.4  
65-75
 
16
 
502 ± 528
 
74.8 ± 12.4
 
pG71D
 
71
 
740
 
90
 
4.9
 

Cohort of the pC282Y homozygous females*

The 4 females with a HAMP gene mutation
Age range, y
No. of patients
Means of SF, μg/L
Means of TS, %
HAMP mutation
Age-D, y
SF, μg/L
TS, %
Phlebotomy IR, g
45-55   37   670 ± 1307   75.5 ± 19.4   pR59G   50   719   97   10.2  
55-65   39   719 ± 1070   72.9 ± 15.7   pG71D   61   852   86   6.5  
     pR56X   62   265   97   3.4  
65-75
 
16
 
502 ± 528
 
74.8 ± 12.4
 
pG71D
 
71
 
740
 
90
 
4.9
 

SF indicates serum ferritin; TS, transferrin saturation; Age-D, age at diagnosis; and phlebotomy IR, phlebotomy iron removed.

*

Excluding those with a HAMP gene mutation.

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