Comparative study of iron indices parameters of pC282Y homozygous females
Cohort of the pC282Y homozygous females* . | . | . | . | The 4 females with a HAMP gene mutation . | . | . | . | . | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Age range, y . | No. of patients . | Means of SF, μg/L . | Means of TS, % . | HAMP mutation . | Age-D, y . | SF, μg/L . | TS, % . | Phlebotomy IR, g . | |||||||
45-55 | 37 | 670 ± 1307 | 75.5 ± 19.4 | pR59G | 50 | 719 | 97 | 10.2 | |||||||
55-65 | 39 | 719 ± 1070 | 72.9 ± 15.7 | pG71D | 61 | 852 | 86 | 6.5 | |||||||
pR56X | 62 | 265 | 97 | 3.4 | |||||||||||
65-75 | 16 | 502 ± 528 | 74.8 ± 12.4 | pG71D | 71 | 740 | 90 | 4.9 |
Cohort of the pC282Y homozygous females* . | . | . | . | The 4 females with a HAMP gene mutation . | . | . | . | . | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Age range, y . | No. of patients . | Means of SF, μg/L . | Means of TS, % . | HAMP mutation . | Age-D, y . | SF, μg/L . | TS, % . | Phlebotomy IR, g . | |||||||
45-55 | 37 | 670 ± 1307 | 75.5 ± 19.4 | pR59G | 50 | 719 | 97 | 10.2 | |||||||
55-65 | 39 | 719 ± 1070 | 72.9 ± 15.7 | pG71D | 61 | 852 | 86 | 6.5 | |||||||
pR56X | 62 | 265 | 97 | 3.4 | |||||||||||
65-75 | 16 | 502 ± 528 | 74.8 ± 12.4 | pG71D | 71 | 740 | 90 | 4.9 |
SF indicates serum ferritin; TS, transferrin saturation; Age-D, age at diagnosis; and phlebotomy IR, phlebotomy iron removed.
Excluding those with a HAMP gene mutation.