Statistical values for significant linkage obtained from the whole genome scan with (BALB/cJ × BXH-2)F2 infected with M bovis (BCG) using spleen index as a phenotypic trait (n = 187)
Markers . | Distance from telomere, cM* . | B6/B6,†high to low . | B6/A + A/A,†high to low . | χ2 . | LOD . |
|---|---|---|---|---|---|
| D8Mit155 | 0.0 | 15:35 | 32:105 | — | — |
| D8Mit289 | 8.7 | 14:38 | 33:102 | — | — |
| D8Mit357 | 24 | 16:32 | 31:108 | — | — |
| D8Mit25 | 33.9 | 20:31 | 27:109 | 7.7 | 1.7 |
| D8Mit250 | 42.6 | 23:30 | 24:110 | 13.0 | 2.8 |
| D8Mit86 | 54.6 | 29:14 | 18:126 | 50.1 | 10.9 |
| D8Mit200 | 60.1 | 36:9 | 11:131 | 114.1 | 24.8 |
| D8Mit13‡ | 68.9 | 41:2 | 6:138 | 202.9 | 44.1‡ |
| D8Mit326 | 74.3 | 39:3 | 8:137 | 180.8 | 39.3 |
Markers . | Distance from telomere, cM* . | B6/B6,†high to low . | B6/A + A/A,†high to low . | χ2 . | LOD . |
|---|---|---|---|---|---|
| D8Mit155 | 0.0 | 15:35 | 32:105 | — | — |
| D8Mit289 | 8.7 | 14:38 | 33:102 | — | — |
| D8Mit357 | 24 | 16:32 | 31:108 | — | — |
| D8Mit25 | 33.9 | 20:31 | 27:109 | 7.7 | 1.7 |
| D8Mit250 | 42.6 | 23:30 | 24:110 | 13.0 | 2.8 |
| D8Mit86 | 54.6 | 29:14 | 18:126 | 50.1 | 10.9 |
| D8Mit200 | 60.1 | 36:9 | 11:131 | 114.1 | 24.8 |
| D8Mit13‡ | 68.9 | 41:2 | 6:138 | 202.9 | 44.1‡ |
| D8Mit326 | 74.3 | 39:3 | 8:137 | 180.8 | 39.3 |
— indicates not significant.
The chromosome position of each marker is expressed as distance from the telomere (shown in cM) and is from the MIT Centre for Genome Research (http://www-genome.wi.mit.edu/cgi-bin/mouse/index)
F2 animals were divided according to their allelic combination at D8mit13 or D8Mit14, derived from C57BL/6J (B6; derived from BXH-2), BALB/cJ, or A/J (A). The ratio of animals with low (< 0.8) or high (≥ 0.8) spleen index is shown along with the relevant statistics to demonstrate significance
Highest LOD score