Table 5.

BCR/ABL transcript level in the patients who achieved a complete and stable CgR

Transcript level, median
No. of cases with a transcript less than 0.00001/ no. of analyzed cases
Time
Early
Late
Total
Early
Late
Total
Baseline   0.2330   0.2490   0.2330   0/43   0/18   0/61  
3 mo   0.0039   0.0213   0.0049   8/38   2/19   10/57  
6 mo   0.0003   0.0046   0.0009   10/39   2/12   12/57  
12 mo   0.0005   0.0034   0.0008   6/37   2/18   8/55  
24 mo
 		 0.0001
 		 0.0002
 		 0.0001
 		 16/30
 		 6/16
 		 22/46
 
Transcript level, median
No. of cases with a transcript less than 0.00001/ no. of analyzed cases
Time
Early
Late
Total
Early
Late
Total
Baseline   0.2330   0.2490   0.2330   0/43   0/18   0/61  
3 mo   0.0039   0.0213   0.0049   8/38   2/19   10/57  
6 mo   0.0003   0.0046   0.0009   10/39   2/12   12/57  
12 mo   0.0005   0.0034   0.0008   6/37   2/18   8/55  
24 mo
 		 0.0001
 		 0.0002
 		 0.0001
 		 16/30
 		 6/16
 		 22/46
 

Complete and stable CgR achieved either early (in 3 or 6 months) or late (in 9 or 12 months). Also listed are the patients in whom the transcript level was below the sensitivity of the method (BCR/ABL to β2M ratio × 100 ≤ 0.00001). Notice that molecular data were missing in 15 patients at baseline and in 30 patients after 24 months.

View Large
Close Modal
This Feature Is Available To Subscribers Only

or Create an Account

Close Modal
Close Modal