Table 1. Quantification of splenic... | American Society of Hematology

Table 1.

Quantification of splenic lymphoid cell populations

	Mouse strain
Cell phenotype	C57BL/6	*Eμ-Bcl2* 22**	*Eμ-Bcl2* 36**	VavP-Bcl2
B220⁺	150 ± 10	520 ± 120	260 ± 20^*	780 ± 60†
CD4⁺	30 ± 3	53 ± 13^*	38 ± 5^*	170 ± 20†
CD8⁺	26 ± 3	35 ± 8^*	39 ± 2^*	88 ± 11†
Ratio of CD4:CD8	1.2 ± 0.1	1.3 ± 0.2^*	0.9 ± 0.1^*	2.1 ± 0.2†
Ratio of CD4:B220	0.20 ± 0.01	0.11 ± 0.01‡	0.15 ± 0.02‡	0.21 ± 0.01^*

	Mouse strain
Cell phenotype	C57BL/6	*Eμ-Bcl2* 22**	*Eμ-Bcl2* 36**	VavP-Bcl2
B220⁺	150 ± 10	520 ± 120	260 ± 20^*	780 ± 60†
CD4⁺	30 ± 3	53 ± 13^*	38 ± 5^*	170 ± 20†
CD8⁺	26 ± 3	35 ± 8^*	39 ± 2^*	88 ± 11†
Ratio of CD4:CD8	1.2 ± 0.1	1.3 ± 0.2^*	0.9 ± 0.1^*	2.1 ± 0.2†
Ratio of CD4:B220	0.20 ± 0.01	0.11 ± 0.01‡	0.15 ± 0.02‡	0.21 ± 0.01^*

Mean cell number × 10⁶ ± SEM per spleen. For C57BL/6, n = 10; for Eμ-Bcl2 22, n = 5; for Eμ-Bcl2 36, n = 5; and for VavP-Bcl2, n = 16.

Not different from C57BL/6 by Fisher's PLSD P > 0.45

Different from all other groups by Fisher's PLSD P < 0.03

Different from C57BL/6 and VavP Bcl2 by Fisher's PLSD P < 0.03