Table 7.

Memory antibody responses to ϕX174 immunization in JAK3-deficient SCID patients on IVIG therapy

Response type
Patient no.
No. of immunizations
Peak titer, Kv*
IgM, %
IgG, %†
3   2   594   98   2  
4   4   466   98.4   1.6  
6   7   27.9   99.7   0.3  
8   5   457   99   1  
9   5   194   97.9   2.1  
10
 		 3
 		 360
 		 99.5
 		 0.5
 
Response type
Patient no.
No. of immunizations
Peak titer, Kv*
IgM, %
IgG, %†
3   2   594   98   2  
4   4   466   98.4   1.6  
6   7   27.9   99.7   0.3  
8   5   457   99   1  
9   5   194   97.9   2.1  
10
 		 3
 		 360
 		 99.5
 		 0.5
 

Kv is the calculated rate of phage inactivation.

*

Peak Kv values are normal for all patients with the exception of patient 6, whose value is low-normal.

†

Normal = 56 ± 24.

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