Table 5. Most recent proliferative... | American Society of Hematology

Table 5.

Most recent proliferative responses in JAK3-deficient patients after transplantation

			Mitogen responses^*				Antigen-specific response^*
Patient no.	Time of study†	Medium	PHA	ConA	PWM	Medium	Tetanus
Patient no.
1	3	847	203 595	235 347	149 399	1069	28 935
2	18	2757	243 707	420 456	138 425	2752	104 412
3	12	2328	245 210	203 535	110 730	2518	5054
4	4	251	115 436	85 833	27 530	1185	4267
5	10	324	160 925	129 705	187 185	3128	177 910
6	8	785	260 860	186 940	192 166	2991	29 775
8	10	681	143 126	83 173	77 100	1178	12 794
9	9	346	125 060	72 195	53 130	457	13 219
10	7	531	133 790	135 770	114 156	10 432	17 803
Mean ± SD	9 ± 4	983 ± 914	181 301 ± 57 485	172 550 ± 109 164	116 646 ± 56 796	2857 ± 2831	43 797 ± 55 491
Normal‡	NA	693 ± 825	222 330 ± 50 643	208 534 ± 52 592	135 520 ± 35 077	3840 ± 6306	72 371 ± 50 693

			Mitogen responses^*				Antigen-specific response^*
Patient no.	Time of study†	Medium	PHA	ConA	PWM	Medium	Tetanus
Patient no.
1	3	847	203 595	235 347	149 399	1069	28 935
2	18	2757	243 707	420 456	138 425	2752	104 412
3	12	2328	245 210	203 535	110 730	2518	5054
4	4	251	115 436	85 833	27 530	1185	4267
5	10	324	160 925	129 705	187 185	3128	177 910
6	8	785	260 860	186 940	192 166	2991	29 775
8	10	681	143 126	83 173	77 100	1178	12 794
9	9	346	125 060	72 195	53 130	457	13 219
10	7	531	133 790	135 770	114 156	10 432	17 803
Mean ± SD	9 ± 4	983 ± 914	181 301 ± 57 485	172 550 ± 109 164	116 646 ± 56 796	2857 ± 2831	43 797 ± 55 491
Normal‡	NA	693 ± 825	222 330 ± 50 643	208 534 ± 52 592	135 520 ± 35 077	3840 ± 6306	72 371 ± 50 693

Abbreviations are explained in a footnote to Table 1.

NA indicates not applicable.

Counts per minute [³H]thymidine incorporation.

Number of years after most recent transplantation when experiments were performed (median = 9 years).

Values for 167 control subjects expressed as means ± SD.