Table 3.

Correlation of REL copy number and REL nuclear accumulation with clinical features




REL copy no.

% REL-positive nuclei
Patient characteristics
All patients
Less than 4*
4 or more
50% or less
70% or more§
Male/female, no.   29/17   21/13   5/4   15/7   10/7  
Median age, y (range)   62 (25-84)   63 (29-84)   63 (41-75)   63 (29-79)   67 (25-80)  
Stage      
    I, no. (%)   12 (26)   10 (29)   2 (22)   4 (18)   6 (35)  
    II, no. (%)   14 (30.5)   8 (24)   5 (56)   7 (32)   5 (29)  
    III, no. (%)   6 (13)   4 (12)   0 (0)   3 (14)   3 (18)  
    IV, no. (%)   14 (30.5)   12 (35)   2 (22)   8 (36)   3 (18)  
Pure EN disease, no. (%)   10 (22)   7 (21)   3 (33)   4 (18)   4 (24)  
IPI risk group      
    Low, no. (%)   13 (29)   10 (30.5)   1 (11)   7 (32)   6 (35)  
    Low-intermediate, no. (%)   13 (29)   8 (24)   5 (56)   6 (27)   4 (23.5)  
    High-intermediate, no. (%)   7 (15.5)   6 (18)   1 (11)   3 (14)   3 (18)  
    High, no. (%)
 
12 (26.5)
 
9 (27.5)
 
2 (22)
 
6 (27)
 
4 (23.5)
 



REL copy no.

% REL-positive nuclei
Patient characteristics
All patients
Less than 4*
4 or more
50% or less
70% or more§
Male/female, no.   29/17   21/13   5/4   15/7   10/7  
Median age, y (range)   62 (25-84)   63 (29-84)   63 (41-75)   63 (29-79)   67 (25-80)  
Stage      
    I, no. (%)   12 (26)   10 (29)   2 (22)   4 (18)   6 (35)  
    II, no. (%)   14 (30.5)   8 (24)   5 (56)   7 (32)   5 (29)  
    III, no. (%)   6 (13)   4 (12)   0 (0)   3 (14)   3 (18)  
    IV, no. (%)   14 (30.5)   12 (35)   2 (22)   8 (36)   3 (18)  
Pure EN disease, no. (%)   10 (22)   7 (21)   3 (33)   4 (18)   4 (24)  
IPI risk group      
    Low, no. (%)   13 (29)   10 (30.5)   1 (11)   7 (32)   6 (35)  
    Low-intermediate, no. (%)   13 (29)   8 (24)   5 (56)   6 (27)   4 (23.5)  
    High-intermediate, no. (%)   7 (15.5)   6 (18)   1 (11)   3 (14)   3 (18)  
    High, no. (%)
 
12 (26.5)
 
9 (27.5)
 
2 (22)
 
6 (27)
 
4 (23.5)
 

EN indicates extranodal disease.

*

n = 34.

n = 9.

n = 22.

§

n = 17.

One patient had insufficient clinical data to determine IPI score.

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