Table 3. IC 50 values for chlorambucil... | American Society of Hematology

Table 3.

IC₅₀ values for chlorambucil or fludarabine alone or in the presence of HMA

Patient no.	IC₅₀, μM
Patient no.		HMA	Chl	Chl/HMA, 100:1	Flu	Flu/HMA, 10:1
1	1.2	24.2	23	3.3	4
2	0.45	61.8	12.6*	1.2	0.77
3	0.86	167	8.9*	5.4	1.3
4	0.46	68.6	16.3*	3.3	1.6
5	0.31	27.8	18.4	2.0	1.1
6	0.65	50.9	26.6	7.5	3.3†
7	0.09	8.8	5.1	0.76	0.27†
8	0.541	60.5	20.7†	1.2	1.3
9	0.04	20.2	4.0*	0.38	0.29
10	0.14	13.2	14.6	2.6	1.9
11	0.24	13.3	10.8	1.1	0.6
12	0.16	10.7	6.2	0.68	0.73
13	0.06	5.3	4.1	0.77	0.34

Patient no.	IC₅₀, μM
Patient no.		HMA	Chl	Chl/HMA, 100:1	Flu	Flu/HMA, 10:1
1	1.2	24.2	23	3.3	4
2	0.45	61.8	12.6*	1.2	0.77
3	0.86	167	8.9*	5.4	1.3
4	0.46	68.6	16.3*	3.3	1.6
5	0.31	27.8	18.4	2.0	1.1
6	0.65	50.9	26.6	7.5	3.3†
7	0.09	8.8	5.1	0.76	0.27†
8	0.541	60.5	20.7†	1.2	1.3
9	0.04	20.2	4.0*	0.38	0.29
10	0.14	13.2	14.6	2.6	1.9
11	0.24	13.3	10.8	1.1	0.6
12	0.16	10.7	6.2	0.68	0.73
13	0.06	5.3	4.1	0.77	0.34

The patient numbers are as described in the first column of Table 2.

Isolates whose IC₅₀ was decreased by more than 75% in the presence of HMA.

Isolates whose IC₅₀ was decreased by more than 50% in the presence of HMA.