Demographic and baseline characteristics of the study population
. | LPA96 study, N = 175 . | . | LPA99 study, N = 251 . | . | . | ||
|---|---|---|---|---|---|---|---|
| Characteristic . | Median (range) . | No. (%) . | Median (range) . | No. (%) . | P . | ||
| Age, y | 40 (2-73) | 39 (2-81) | .4 | ||||
| 15 or younger | 11 (6.3) | 28 (11.1) | |||||
| 16-40 | 77 (44.0) | 106 (42.1) | |||||
| 41-60 | 58 (33.1) | 72 (28.7) | |||||
| 61-70 | 19 (10.9) | 33 (13.1) | |||||
| 71 or older | 10 (5.7) | 12 (4.8) | |||||
| Sex | .01 | ||||||
| Male | 103 (58.9) | 116 (46.2) | |||||
| Female | 72 (41.1) | 135 (53.8) | |||||
| WBC count, × 109/L | 2.1 (0.3-210) | 2.5 (0.3-235) | .8 | ||||
| Less than 3.5 | 108 (61.7) | 145 (57.8) | |||||
| 3.5-10 | 21 (12.0) | 35 (13.9) | |||||
| 10-50 | 33 (18.9) | 50 (19.9) | |||||
| 50 or higher | 13 (7.4) | 21 (8.4) | |||||
| Patelet count, × 109/L | 20 (1-161) | 22 (1-183) | .7 | ||||
| Less than 10 | 38 (21.7) | 46 (18.3) | |||||
| 11-40 | 97 (55.4) | 142 (56.6) | |||||
| 40 or higher | 40 (22.9) | 63 (25.1) | |||||
| Hemoglobin, g/L (range) | 94 (43-152) | 92 (30-169) | |||||
| Morphologic subtype | .5 | ||||||
| Hypergranular | 144 (82.3) | 201 (80.1) | |||||
| Microgranular | 31 (17.7) | 50 (19.9) | |||||
| PML/RARα isoform | .4 | ||||||
| BCR1/BCR2 | 94 (55.9) | 128 (56.4) | |||||
| BCR3 | 74 (44.1) | 99 (43.6) | |||||
. | LPA96 study, N = 175 . | . | LPA99 study, N = 251 . | . | . | ||
|---|---|---|---|---|---|---|---|
| Characteristic . | Median (range) . | No. (%) . | Median (range) . | No. (%) . | P . | ||
| Age, y | 40 (2-73) | 39 (2-81) | .4 | ||||
| 15 or younger | 11 (6.3) | 28 (11.1) | |||||
| 16-40 | 77 (44.0) | 106 (42.1) | |||||
| 41-60 | 58 (33.1) | 72 (28.7) | |||||
| 61-70 | 19 (10.9) | 33 (13.1) | |||||
| 71 or older | 10 (5.7) | 12 (4.8) | |||||
| Sex | .01 | ||||||
| Male | 103 (58.9) | 116 (46.2) | |||||
| Female | 72 (41.1) | 135 (53.8) | |||||
| WBC count, × 109/L | 2.1 (0.3-210) | 2.5 (0.3-235) | .8 | ||||
| Less than 3.5 | 108 (61.7) | 145 (57.8) | |||||
| 3.5-10 | 21 (12.0) | 35 (13.9) | |||||
| 10-50 | 33 (18.9) | 50 (19.9) | |||||
| 50 or higher | 13 (7.4) | 21 (8.4) | |||||
| Patelet count, × 109/L | 20 (1-161) | 22 (1-183) | .7 | ||||
| Less than 10 | 38 (21.7) | 46 (18.3) | |||||
| 11-40 | 97 (55.4) | 142 (56.6) | |||||
| 40 or higher | 40 (22.9) | 63 (25.1) | |||||
| Hemoglobin, g/L (range) | 94 (43-152) | 92 (30-169) | |||||
| Morphologic subtype | .5 | ||||||
| Hypergranular | 144 (82.3) | 201 (80.1) | |||||
| Microgranular | 31 (17.7) | 50 (19.9) | |||||
| PML/RARα isoform | .4 | ||||||
| BCR1/BCR2 | 94 (55.9) | 128 (56.4) | |||||
| BCR3 | 74 (44.1) | 99 (43.6) | |||||