Cumulative quantitation of donor cell distribution using RQ-STR analysis in double cord transplantation with MSC coinfusion
STR . | Donor A, % STR* . | Donor B, % STR* . | Donor cell ratio . |
|---|---|---|---|
| Type 1 | 66.7 ± 4.4 | 33.3 ± 4.4 | 2.0:1 |
| Type 2 | 63.7 ± 3.9 | 36.3 ± 3.9 | 1.8:1 |
| Total | 66.5 ± 4.4 | 33.5 ± 4.4 | 2.0:1 |
STR . | Donor A, % STR* . | Donor B, % STR* . | Donor cell ratio . |
|---|---|---|---|
| Type 1 | 66.7 ± 4.4 | 33.3 ± 4.4 | 2.0:1 |
| Type 2 | 63.7 ± 3.9 | 36.3 ± 3.9 | 1.8:1 |
| Total | 66.5 ± 4.4 | 33.5 ± 4.4 | 2.0:1 |
n = 8. Data are derived from cohorts that included 4 pairs of UCB units each: one 3-mismatch pair, two 5-mismatch pairs, and one full-mismatch pair. Mononuclear cells equivalent to 3 × 104 CD34+ cells for each UCB were mixed and transplanted with 4 × 104 cultured MSCs. The percentage of donor-specific contribution and the donor cell ratio were calculated as described in Table 1.
Values are presented as mean ± SEM.