Organisms that caused IFIs that occurred while on-treatment
Infection* . | Fluconazole . | Itraconazole† . |
|---|---|---|
| Aspergillosis—total | 17 | 8 |
| A fumigatus | 11 | 5 |
| A species—NOS | 2 | 2 |
| A terreus | 2 | 0 |
| A niger | 1 | 0 |
| Multiple‡ | 1 | 1 |
| Other mold infections—total | 1 | 0 |
| Fusarium species | 1 | 0 |
| Candidemia—total§ | 4 | 3 |
| C glabrata | 1 | 2 |
| C krusei | 1 | 0 |
| C parapsilosis | 2 | 1 |
| C albicans | 0 | 0 |
Infection* . | Fluconazole . | Itraconazole† . |
|---|---|---|
| Aspergillosis—total | 17 | 8 |
| A fumigatus | 11 | 5 |
| A species—NOS | 2 | 2 |
| A terreus | 2 | 0 |
| A niger | 1 | 0 |
| Multiple‡ | 1 | 1 |
| Other mold infections—total | 1 | 0 |
| Fusarium species | 1 | 0 |
| Candidemia—total§ | 4 | 3 |
| C glabrata | 1 | 2 |
| C krusei | 1 | 0 |
| C parapsilosis | 2 | 1 |
| C albicans | 0 | 0 |
NOS indicates not otherwise specified (organism detected by histopathology only).
Only organisms that caused proven or probable IFIs are listed.
One patient developed both aspergillosis and candidemia.
One patient in the itraconazole arm developed a mixed infection with A niger and Cunninghamella, and one fluconazole recipient developed a mixed infection with A fumigatus and A niger.
All Candida species were resistant to fluconazole and itraconazole (data not shown).