Table 1.

Expression of ILT2, HLA-G, and IL-10 in primary cutaneous cytotoxic lymphomas


Case no.

Age, y/sex

TCR gene rearrangement

Disease stage

Immunophenotype

IL T2*(F278)

HLA-G*(4H84)

IL-10*
1   39/F  Vγ1-8, VJ1/2   IVb   TIA1+perforin+GrB+CD4+CD43+CD56+  +   +   +  
2   73/M   Positive  IIb   TIA1+perforin+GrB+CD4+CD43+CD56+  +   -   -  
3   52/F  Positive  IIb   TIA1+perforin+GrB+CD4+CD43+CD56+  +   +   +  
4   69/F   Vγ1-8   Ib   TIA1+perforin-GrB+CD3+CD8+CD43+  +   +   +  
5   39/M   Positive  Ib   TIA1+perforin+GrB-CD2+CD3+CD8+ CD43+  +   +   +  
6   45/M   Vγ1-8   Ib   TIA1+perforin+GrB+CD2+CD3+CD8+ CD43+  +   +   +  
7
 
48/M
 
Vγ1-8 and JP1
 
Ia
 
TIA1+perforin-GrB+CD3+CD8+CD43+
 
+
 
+
 
+
 

Case no.

Age, y/sex

TCR gene rearrangement

Disease stage

Immunophenotype

IL T2*(F278)

HLA-G*(4H84)

IL-10*
1   39/F  Vγ1-8, VJ1/2   IVb   TIA1+perforin+GrB+CD4+CD43+CD56+  +   +   +  
2   73/M   Positive  IIb   TIA1+perforin+GrB+CD4+CD43+CD56+  +   -   -  
3   52/F  Positive  IIb   TIA1+perforin+GrB+CD4+CD43+CD56+  +   +   +  
4   69/F   Vγ1-8   Ib   TIA1+perforin-GrB+CD3+CD8+CD43+  +   +   +  
5   39/M   Positive  Ib   TIA1+perforin+GrB-CD2+CD3+CD8+ CD43+  +   +   +  
6   45/M   Vγ1-8   Ib   TIA1+perforin+GrB+CD2+CD3+CD8+ CD43+  +   +   +  
7
 
48/M
 
Vγ1-8 and JP1
 
Ia
 
TIA1+perforin-GrB+CD3+CD8+CD43+
 
+
 
+
 
+
 

TIA1 indicates T-cell intracellular antigen 1; and GrB, granzyme B.

*

Stainings were done on frozen tissue sections.

Deceased.

Positive, but not further specified.

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