Table 2.

Effect of ITP plasma on megakaryocyte ploidy distribution



Ploidy distribution, % ± SD
Assay
2N
4N
8N
16N
Day 5     
    Control plasma   39.5 ± 1.8   54.3 ± 2.3   5.0 ± 0.6   1.3 ± 0.2  
    ITP-1 plasma   86.2*  12.9*  0.9*  0* 
    ITP-5 plasma   66.5*  31*  2.2*  0.4* 
    ITP-18 plasma   51.9*  43.6*  3.7*  0.9  
Day 7     
    Control   36.9 ± 7.0   49.9 ± 4.8   10.6 ± 1.8   2.4 ± 0.4  
    ITP-1   90.4*  22.8*  0.5*  0.1* 
    ITP-5   73.8*  9.0*  3.1*  0.4* 
    ITP-18   52.3*  39.0*  7.3   1.4* 
Day 10     
    Control   39.5 ± 4.5   42.7 ± 3.2   14.1 ± 1.5   3.2 ± 0.7  
    ITP-1   85.8*  9.7*  0.4*  0* 
    ITP-5   90.0*  12.8*  1.6*  0.2* 
    ITP-18
 
44.5
 
40.4
 
12.3
 
1.4
 


Ploidy distribution, % ± SD
Assay
2N
4N
8N
16N
Day 5     
    Control plasma   39.5 ± 1.8   54.3 ± 2.3   5.0 ± 0.6   1.3 ± 0.2  
    ITP-1 plasma   86.2*  12.9*  0.9*  0* 
    ITP-5 plasma   66.5*  31*  2.2*  0.4* 
    ITP-18 plasma   51.9*  43.6*  3.7*  0.9  
Day 7     
    Control   36.9 ± 7.0   49.9 ± 4.8   10.6 ± 1.8   2.4 ± 0.4  
    ITP-1   90.4*  22.8*  0.5*  0.1* 
    ITP-5   73.8*  9.0*  3.1*  0.4* 
    ITP-18   52.3*  39.0*  7.3   1.4* 
Day 10     
    Control   39.5 ± 4.5   42.7 ± 3.2   14.1 ± 1.5   3.2 ± 0.7  
    ITP-1   85.8*  9.7*  0.4*  0* 
    ITP-5   90.0*  12.8*  1.6*  0.2* 
    ITP-18
 
44.5
 
40.4
 
12.3
 
1.4
 
*

Significant at P < .05.

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