Table 2. Repartition of A3 haplotype in... | American Society of Hematology

Table 2.

Repartition of A3 haplotype in cases and controls in the PATHROS study, in the whole population or according to sex

	Total			Men			Women
	Cases	Controls	Cases	Controls	Cases	Controls
n	338	338	162	162	176	176
Age, mean ± SD, y	48 ± 15	46 ± 13	52 ± 14	49 ± 12	45 ± 14	44 ± 13
No. of subjects with
No A3 allele	249	278	116	136	133	142
1 A3 allele	85	58	45	26	40	32
2 A3 alleles	4	2	1	0	3	2
A3 carriers, %	26.3*	17.7	28.4†	16	24.4‡	19.3
Allele frequency
A3	0.138	0.092	0.145	0.08	0.13	0.1
A1 + A2	0.862	0.908	0.855	0.092	0.87	0.9

	Total			Men			Women
	Cases	Controls	Cases	Controls	Cases	Controls
n	338	338	162	162	176	176
Age, mean ± SD, y	48 ± 15	46 ± 13	52 ± 14	49 ± 12	45 ± 14	44 ± 13
No. of subjects with
No A3 allele	249	278	116	136	133	142
1 A3 allele	85	58	45	26	40	32
2 A3 alleles	4	2	1	0	3	2
A3 carriers, %	26.3*	17.7	28.4†	16	24.4‡	19.3
Allele frequency
A3	0.138	0.092	0.145	0.08	0.13	0.1
A1 + A2	0.862	0.908	0.855	0.092	0.87	0.9

indicates P = .009; †, P = .011; and ‡, P = .3.