Humeral BM clonogenic activity in CFU per 105 MNCs plated
. | Preirradiated . | H6 . | D1 . | D3/D4 . | D42 . | D450 . |
|---|---|---|---|---|---|---|
| Control monkeys | ||||||
| CFU-GMs | 128 ± 56 | 3.5 ± 2.3 | 0.75 ± 0.5 | 0.5 ± 0.5 | 20.5 ± 4.2 | 120 ± 24 |
| BFU-Es | 71.5 ± 18 | 0.75 ± 0.3 | 0 | 0.5 ± 0.3 | 70 ± 26 | 96.5 ± 21 |
| CFU-GEMMs | 48.8 ± 13 | 0.5 ± 0.3 | 0.3 ± 0.3 | 0 | 42.5 ± 27 | 43 ± 11 |
| Cumulated CFUs | 249 ± 77 | 4.75 ± 2.1 | 1 ± 1.1 | 1 ± 1.4 | 133 ± 49 | 259.5 ± 36 |
| 4F-treated monkeys | ||||||
| CFU-GMs | 66 ± 24 | 2.25 ± 1.3 | 10.5 ± 7* | 21.5 ± 13* | 39 ± 11 | 117.3 ± 18 |
| BFU-Es | 46.8 ± 19 | 1.5 ± 1.5 | 1.3 ± 0.5* | 9.3 ± 5.1* | 112.3 ± 32 | 103.5 ± 27 |
| CFU-GEMMs | 50.3 ± 7.7 | 0.3 ± 0.3 | 0.5 ± 1 | 5.3 ± 2.7* | 47.5 ± 13 | 61.3 ± 21 |
| Cumulated CFUs | 163 ± 19 | 4 ± 2.6 | 12.3 ± 7* | 36 ± 12* | 199 ± 54 | 282 ± 54 |
. | Preirradiated . | H6 . | D1 . | D3/D4 . | D42 . | D450 . |
|---|---|---|---|---|---|---|
| Control monkeys | ||||||
| CFU-GMs | 128 ± 56 | 3.5 ± 2.3 | 0.75 ± 0.5 | 0.5 ± 0.5 | 20.5 ± 4.2 | 120 ± 24 |
| BFU-Es | 71.5 ± 18 | 0.75 ± 0.3 | 0 | 0.5 ± 0.3 | 70 ± 26 | 96.5 ± 21 |
| CFU-GEMMs | 48.8 ± 13 | 0.5 ± 0.3 | 0.3 ± 0.3 | 0 | 42.5 ± 27 | 43 ± 11 |
| Cumulated CFUs | 249 ± 77 | 4.75 ± 2.1 | 1 ± 1.1 | 1 ± 1.4 | 133 ± 49 | 259.5 ± 36 |
| 4F-treated monkeys | ||||||
| CFU-GMs | 66 ± 24 | 2.25 ± 1.3 | 10.5 ± 7* | 21.5 ± 13* | 39 ± 11 | 117.3 ± 18 |
| BFU-Es | 46.8 ± 19 | 1.5 ± 1.5 | 1.3 ± 0.5* | 9.3 ± 5.1* | 112.3 ± 32 | 103.5 ± 27 |
| CFU-GEMMs | 50.3 ± 7.7 | 0.3 ± 0.3 | 0.5 ± 1 | 5.3 ± 2.7* | 47.5 ± 13 | 61.3 ± 21 |
| Cumulated CFUs | 163 ± 19 | 4 ± 2.6 | 12.3 ± 7* | 36 ± 12* | 199 ± 54 | 282 ± 54 |
Values presented as mean ± SD. Statistical significance between treated and control groups is expressed. P < .05. H6 indicates 6 hours after TBI.
Significantly different from the control value.