Spearman rank correlation of plasma IL-7 levels with immunologic and viral parameters in SIV-infected macaques
Variable . | P . | Rho . |
|---|---|---|
| TREC+/CD8+ | < .0001 | −0.62 |
| TREC+/CD4+ | .01 | −0.55 |
| CD4 cell count | < .0001 | −0.62 |
| CD8 cell count | .08 | −0.35 |
| CD3 cell count | .002 | −0.52 |
| Percent naive CD4+ | .04 | −0.35 |
| Percent naive CD8+ | .01 | −0.70 |
| Percent Ki67+/CD4+ | .37 | 0.27 |
| Percent Ki67+/CD8+ | .78 | 0.30 |
| B-cell count | .03 | −0.56 |
| Total lymphocytes | .11 | −0.35 |
| Viral load | .54 | 0.27 |
Variable . | P . | Rho . |
|---|---|---|
| TREC+/CD8+ | < .0001 | −0.62 |
| TREC+/CD4+ | .01 | −0.55 |
| CD4 cell count | < .0001 | −0.62 |
| CD8 cell count | .08 | −0.35 |
| CD3 cell count | .002 | −0.52 |
| Percent naive CD4+ | .04 | −0.35 |
| Percent naive CD8+ | .01 | −0.70 |
| Percent Ki67+/CD4+ | .37 | 0.27 |
| Percent Ki67+/CD8+ | .78 | 0.30 |
| B-cell count | .03 | −0.56 |
| Total lymphocytes | .11 | −0.35 |
| Viral load | .54 | 0.27 |
Between 8 and 15 time points throughout the disease course were considered for the correlation of each immune parameter with IL-7 levels in each SIV-infected macaque. The P depicted represents a compilation of the P values from all 6 macaques. P < .05 was considered significant and is given in the table along with median of the 6 Rho values.