Patient's peripheral blood lymphocyte subpopulations 4 months after liver-small bowel transplantation*
. | Total lymphocytes, % . | . | TCRαβ, % . | . | TCRγδ, % . | . | |||
---|---|---|---|---|---|---|---|---|---|
Marker . | Patient . | Control . | Patient . | Control . | Patient . | Control . | |||
CD3+ | 90.5 ± 2.4 | 73.0 ± 2.5 | 23.0 ± 4.7 | 93.0 ± 2.1 | 77.0 ± 4.7 | 6.5 ± 0.7 | |||
CD3+ CD4− CD8− | 61.2 ± 6.2 | 3.1 ± 0.6 | 3.1 ± 2.7 | 0.3 ± 0.0 | 85.7 ± 5.1 | 1.1 ± 0.3 | |||
CD3+ CD4+ CD8− | 1.8 ± 0.8 | 43.0 ± 2.6 | 97.1 ± 1.0 | 99.0 ± 1.6 | 6.3 ± 3.1 | 0.1 ± 0.0 | |||
CD3+ CD4− CD8+ | 28.3 ± 2.5 | 27.0 ± 1.6 | 33.3 ± 2.1 | 93.0 ± 2.3 | 60.0 ± 5.6 | 6.3 ± 1.3 | |||
CD3+ CD4− CD8αβ† | 10.6 ± 1.8 | — | 2.7 ± 0.6 | — | 87.5 ± 5 | — | |||
CD3+ CD4− CD8αα† | 19.6 ± 1.1 | — | 87.7 ± 1.4 | — | 14.6 ± 4.1 | — | |||
CD19+ | 2.2 ± 0.8 | 12.5 ± 1.4 | — | — | — | — | |||
CD56+ | 1.9 ± 1.2 | 13.3 ± 1.6 | — | — | — | — |
. | Total lymphocytes, % . | . | TCRαβ, % . | . | TCRγδ, % . | . | |||
---|---|---|---|---|---|---|---|---|---|
Marker . | Patient . | Control . | Patient . | Control . | Patient . | Control . | |||
CD3+ | 90.5 ± 2.4 | 73.0 ± 2.5 | 23.0 ± 4.7 | 93.0 ± 2.1 | 77.0 ± 4.7 | 6.5 ± 0.7 | |||
CD3+ CD4− CD8− | 61.2 ± 6.2 | 3.1 ± 0.6 | 3.1 ± 2.7 | 0.3 ± 0.0 | 85.7 ± 5.1 | 1.1 ± 0.3 | |||
CD3+ CD4+ CD8− | 1.8 ± 0.8 | 43.0 ± 2.6 | 97.1 ± 1.0 | 99.0 ± 1.6 | 6.3 ± 3.1 | 0.1 ± 0.0 | |||
CD3+ CD4− CD8+ | 28.3 ± 2.5 | 27.0 ± 1.6 | 33.3 ± 2.1 | 93.0 ± 2.3 | 60.0 ± 5.6 | 6.3 ± 1.3 | |||
CD3+ CD4− CD8αβ† | 10.6 ± 1.8 | — | 2.7 ± 0.6 | — | 87.5 ± 5 | — | |||
CD3+ CD4− CD8αα† | 19.6 ± 1.1 | — | 87.7 ± 1.4 | — | 14.6 ± 4.1 | — | |||
CD19+ | 2.2 ± 0.8 | 12.5 ± 1.4 | — | — | — | — | |||
CD56+ | 1.9 ± 1.2 | 13.3 ± 1.6 | — | — | — | — |
Values presented as mean ± standard error of the mean (SEM). CD indicates cluster of differentiation; TCR, T-cell receptor; and —, not assessed.
Absolute lymphocyte number 1.65 × 109/L. Ninety-nine percent of CD3+ cells and 45% of CD19+ cells were of donor origin at the time of this analysis.
CD8αβ and CD8αα frequencies were not assessed on the control population.