Profile of T-cell subsets in patients with chromosome 22q 11.2 deletion syndrome
. | 0 to 12 months of age . | 18 to 50 years of age . |
---|---|---|
Patients* | ||
Mean CD3 count, cells/mm3 | 1996 | 1288 |
Range of CD3 counts, cells/mm3 | 98-5730 | 645-2709 |
Patients below lower limit of normal in CD3 count, % | 85 | 47 |
Mean CD4 count, cells/mm3 | 1380 | 765 |
Range of CD4 counts, cells/mm3 | 39-3704 | 433-1591 |
Patients below lower limit of normal in CD4 count, % | 88 | 47 |
Mean CD8 count, cells/mm3 | 550 | 467 |
Range of CD8 counts, cells/mm3 | 39-2013 | 136-1161 |
Patients below lower limit of normal in CD8 count, % | 91 | 50 |
Controls† | ||
Mean CD3 count, cells/mm3 | 3889 | 1497 |
Mean CD4 count, cells/mm3 | 2781 | 945 |
Mean CD8 count, cells/mm3 | 993 | 512 |
. | 0 to 12 months of age . | 18 to 50 years of age . |
---|---|---|
Patients* | ||
Mean CD3 count, cells/mm3 | 1996 | 1288 |
Range of CD3 counts, cells/mm3 | 98-5730 | 645-2709 |
Patients below lower limit of normal in CD3 count, % | 85 | 47 |
Mean CD4 count, cells/mm3 | 1380 | 765 |
Range of CD4 counts, cells/mm3 | 39-3704 | 433-1591 |
Patients below lower limit of normal in CD4 count, % | 88 | 47 |
Mean CD8 count, cells/mm3 | 550 | 467 |
Range of CD8 counts, cells/mm3 | 39-2013 | 136-1161 |
Patients below lower limit of normal in CD8 count, % | 91 | 50 |
Controls† | ||
Mean CD3 count, cells/mm3 | 3889 | 1497 |
Mean CD4 count, cells/mm3 | 2781 | 945 |
Mean CD8 count, cells/mm3 | 993 | 512 |