Table 1.

Profile of T-cell subsets in patients with chromosome 22q 11.2 deletion syndrome




0 to 12 months of age

18 to 50 years of age
Patients*   
Mean CD3 count, cells/mm3  1996   1288  
Range of CD3 counts, cells/mm3  98-5730   645-2709  
Patients below lower limit of normal in CD3 count, %   85   47  
Mean CD4 count, cells/mm3  1380   765  
Range of CD4 counts, cells/mm3  39-3704   433-1591  
Patients below lower limit of normal in CD4 count, %   88   47  
Mean CD8 count, cells/mm3  550   467  
Range of CD8 counts, cells/mm3  39-2013   136-1161  
Patients below lower limit of normal in CD8 count, %   91   50  
Controls   
Mean CD3 count, cells/mm3  3889   1497  
Mean CD4 count, cells/mm3  2781   945  
Mean CD8 count, cells/mm3
 
993
 
512
 



0 to 12 months of age

18 to 50 years of age
Patients*   
Mean CD3 count, cells/mm3  1996   1288  
Range of CD3 counts, cells/mm3  98-5730   645-2709  
Patients below lower limit of normal in CD3 count, %   85   47  
Mean CD4 count, cells/mm3  1380   765  
Range of CD4 counts, cells/mm3  39-3704   433-1591  
Patients below lower limit of normal in CD4 count, %   88   47  
Mean CD8 count, cells/mm3  550   467  
Range of CD8 counts, cells/mm3  39-2013   136-1161  
Patients below lower limit of normal in CD8 count, %   91   50  
Controls   
Mean CD3 count, cells/mm3  3889   1497  
Mean CD4 count, cells/mm3  2781   945  
Mean CD8 count, cells/mm3
 
993
 
512
 
*

For patients 0 to 12 months of age, n = 138; for 18 to 50 years of age, n = 36.

For controls 0 to 12 months of age, n = 31; for 18 to 50 years of age, n = 30.

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