GP lbα genotypes and CHD
. | All* . | . | . | Whites† . | . | . | African Americans‡ . | . | . | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Genotype . | CHD, no. . | Non-CHD, no. . | RH (95% CI) . | CHD, no. . | Non-CHD, no. . | RH (95% CI) . | CHD, no. . | Non-CHD, no. . | RH (95% CI) . | ||||||
| BC+BB | 61 | 50 | 1.6 (0.8-3.2) | 26 | 31 | 1.1 (0.4-2.6) | 35 | 19 | 5.6 (1.2-26.6) | ||||||
| CC | 239 | 279 | & | 206 | 219 | & | 33 | 60 | & | ||||||
| CD+DD | 45 | 30 | 1.8 (0.87-3.6) | 33 | 25 | 1.4 (0.8-3.1) | 12 | 5 | 21.7 (4.3-108.8) | ||||||
. | All* . | . | . | Whites† . | . | . | African Americans‡ . | . | . | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Genotype . | CHD, no. . | Non-CHD, no. . | RH (95% CI) . | CHD, no. . | Non-CHD, no. . | RH (95% CI) . | CHD, no. . | Non-CHD, no. . | RH (95% CI) . | ||||||
| BC+BB | 61 | 50 | 1.6 (0.8-3.2) | 26 | 31 | 1.1 (0.4-2.6) | 35 | 19 | 5.6 (1.2-26.6) | ||||||
| CC | 239 | 279 | & | 206 | 219 | & | 33 | 60 | & | ||||||
| CD+DD | 45 | 30 | 1.8 (0.87-3.6) | 33 | 25 | 1.4 (0.8-3.1) | 12 | 5 | 21.7 (4.3-108.8) | ||||||
RH (95% CI) indicates relative hazard (95% confidence interval), adjusted for age, sex, race, hypertension, diabetes mellitus, total cholesterol, HDL-C, smoking, and alcohol intake; &, reference value in calculation of adjusted relative hazard.
P values calculated for the comparison of GP lbα genotypes against incident CHD status. P is computed by adjusting the effects of age, sex, and race for all subjects, and by adjusting the effects of age and sex for whites and African Americans. In African Americans, P = .014 for CC versus BC+BB and P = .0001 for CC versus CD+DD.
P = .101.
P = .871.
P < .0001.