Table 1.

Age-, race-, and sex-adjusted means and proportions of CHD risk factors in the cohort random sample in relation to the GP lbα genotypes



Genotypes

Variable
BC+BB
CC
CD+DD
P
Hypertension, %   24   27   19   .655  
Diabetes mellitus, %   3   6   9   .675  
Systolic blood pressure, mm Hg   117   119   118   .835  
Total cholesterol level, mM/L   5.28   5.62   5.41   .204  
Triglyceride level, mmol/L   1.39   1.39   1.40   .987  
HDL-C level, mmol/L   1.45   1.40   1.32   .453  
LDL-C level, mmol/L   3.21   3.60   3.44   .498  
Fibrinogen level, μmol/L   8.47   8.94   8.64   .475  
VWF, %   133   118   102   .170  
Cigarette-years   272   234   210   .693  
Ethanol intake, g/wk   32   30   31   .987  
Waist-to-hip ratio   0.89   0.92   0.91   .260  
Age, y   55   54   54   .482  
Males, %   40   43   47   .906  
African Americans, %
 
39
 
22
 
5
 
.003*
 


Genotypes

Variable
BC+BB
CC
CD+DD
P
Hypertension, %   24   27   19   .655  
Diabetes mellitus, %   3   6   9   .675  
Systolic blood pressure, mm Hg   117   119   118   .835  
Total cholesterol level, mM/L   5.28   5.62   5.41   .204  
Triglyceride level, mmol/L   1.39   1.39   1.40   .987  
HDL-C level, mmol/L   1.45   1.40   1.32   .453  
LDL-C level, mmol/L   3.21   3.60   3.44   .498  
Fibrinogen level, μmol/L   8.47   8.94   8.64   .475  
VWF, %   133   118   102   .170  
Cigarette-years   272   234   210   .693  
Ethanol intake, g/wk   32   30   31   .987  
Waist-to-hip ratio   0.89   0.92   0.91   .260  
Age, y   55   54   54   .482  
Males, %   40   43   47   .906  
African Americans, %
 
39
 
22
 
5
 
.003*
 

HDL-C indicates high-density lipoprotein cholesterol; and LDL-C, low-density lipoprotein cholesterol.

*

P values for BC+BB versus CC, BC+BB versus CD+DD, and CC versus CD+DD are .074, .0001, and .009, respectively.

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