GVHD-associated factors compared with quartile of donor graft T-cell CD25 expression
. | CD4+CD25+ T cells . | . | . | CD8+CD25+ T cells . | . | . | ||||
|---|---|---|---|---|---|---|---|---|---|---|
. | Lowest quartile* . | Quartiles 2-4† . | P . | Lowest quartile* . | Quartiles 2-4† . | P . | ||||
| Conditioning intensity, n (%) | .9 | .6 | ||||||||
| Myeloablative | 4 (27) | 16 (36) | — | 4 (27) | 16 (36) | — | ||||
| Reduced-intensity | 6 (40) | 14 (31) | — | 7 (47) | 13 (29) | — | ||||
| Nonmyeloablative | 5 (33) | 15 (33) | — | 4 (27) | 16 (36) | — | ||||
| Sex compatibility, n (%) | .7 | .7 | ||||||||
| Female donor of male recipient | 3 (20) | 13 (29) | — | 3 (20) | 13 (29) | — | ||||
| Others | 12 (80) | 32 (71) | — | 12 (80) | 32 (71) | — | ||||
| Patient age, y, median (range) | 48 (10-72) | 45 (21-70) | .6 | 49 (10-66) | 45 (21-72) | .6 | ||||
| Donor age, y, median (range) | 49 (17-76) | 43 (16-70) | .2 | 51 (17-65) | 43 (16-76) | .2 | ||||
| Infused nucleated cells, × 108/kg, median (range) | 6.7 (1-20.2) | 5.9 (2.4-18.3) | .5 | 7.1 (1-9.8) | 5.9 (2.4-20.2) | .4 | ||||
| Infused CD34+ cells, × 106/kg, median (range) | 4.3 (2.6-6.9) | 4.7 (2.2-8) | .2 | 4.4 (2.6-6.9) | 4.7 (2.2-8) | .8 | ||||
| Infused CD3+ cells, × 106/kg, median (range) | 180 (79-360) | 176 (41-2342) | .6 | 180 (79-360) | 175 (41-559) | .6 | ||||
. | CD4+CD25+ T cells . | . | . | CD8+CD25+ T cells . | . | . | ||||
|---|---|---|---|---|---|---|---|---|---|---|
. | Lowest quartile* . | Quartiles 2-4† . | P . | Lowest quartile* . | Quartiles 2-4† . | P . | ||||
| Conditioning intensity, n (%) | .9 | .6 | ||||||||
| Myeloablative | 4 (27) | 16 (36) | — | 4 (27) | 16 (36) | — | ||||
| Reduced-intensity | 6 (40) | 14 (31) | — | 7 (47) | 13 (29) | — | ||||
| Nonmyeloablative | 5 (33) | 15 (33) | — | 4 (27) | 16 (36) | — | ||||
| Sex compatibility, n (%) | .7 | .7 | ||||||||
| Female donor of male recipient | 3 (20) | 13 (29) | — | 3 (20) | 13 (29) | — | ||||
| Others | 12 (80) | 32 (71) | — | 12 (80) | 32 (71) | — | ||||
| Patient age, y, median (range) | 48 (10-72) | 45 (21-70) | .6 | 49 (10-66) | 45 (21-72) | .6 | ||||
| Donor age, y, median (range) | 49 (17-76) | 43 (16-70) | .2 | 51 (17-65) | 43 (16-76) | .2 | ||||
| Infused nucleated cells, × 108/kg, median (range) | 6.7 (1-20.2) | 5.9 (2.4-18.3) | .5 | 7.1 (1-9.8) | 5.9 (2.4-20.2) | .4 | ||||
| Infused CD34+ cells, × 106/kg, median (range) | 4.3 (2.6-6.9) | 4.7 (2.2-8) | .2 | 4.4 (2.6-6.9) | 4.7 (2.2-8) | .8 | ||||
| Infused CD3+ cells, × 106/kg, median (range) | 180 (79-360) | 176 (41-2342) | .6 | 180 (79-360) | 175 (41-559) | .6 | ||||