Genotypes of litters born by intercrossing heterozygous parents
AML1+/WT crossing . | . | . | . | AML1+/Δ446crossing . | . | . | . | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Clone . | +/+ . | +/WT . | WT/WT . | Clone . | +/+ . | +/Δ446 . | Δ446/Δ446 . | ||||||
| 164 | 46 | 68 | 53 | 804 | 60 | 78 | 46 | ||||||
| 734 | 26 | 72 | 31 | 807 | 23 | 60 | 26 | ||||||
AML1+/WT crossing . | . | . | . | AML1+/Δ446crossing . | . | . | . | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Clone . | +/+ . | +/WT . | WT/WT . | Clone . | +/+ . | +/Δ446 . | Δ446/Δ446 . | ||||||
| 164 | 46 | 68 | 53 | 804 | 60 | 78 | 46 | ||||||
| 734 | 26 | 72 | 31 | 807 | 23 | 60 | 26 | ||||||
+ indicates wild-type allele for the AML1 gene; WT, knock-in allele with full-length (451-residue) cDNA of AML1 gene; and Δ446, knock-in allele with Δ446-deletion mutant cDNA of AML1 gene.