Table 3.

Pathologic features on 95 duodenal biopsy specimens




Pathologic GvHD, % n = 71

No evidence of GvHD, % n = 24
Edema   
    Yes   75   50  
    Moderate   44   8  
    Severe   15   0  
Eosinophils   
    Yes   52   4  
    More than 10/field   20   0  
    More than 20/field   4   0  
Neutrophils   
    Yes   55   13  
    More than 10/field   18   4  
    More than 20/field   6   4  
Lymphocytes   
    Yes   100   96  
    More than 20/field   76   17  
    More than 40/field   37   4  
Macrophages   
    Yes   89   71  
    More than 10/field   38   0  
    More than 20/field   13   0  
Apoptotic epithelial cells by TUNEL   
    Yes   99   8  
    More than 5/field   38   0  
    More than 10/field   8   0  
Apoptotic cells within the infiltrate by TUNEL   
    Yes   63   13  
    More than 5/field   11   4  
Fas expression within the cellular infiltrate   
    Yes   73   4  
    More than 5 cells/field   24   0  
TNFR-1   
    Yes   76   13  
    More than 5 cells/field   6   0  
TNFR-2   
    Yes   77   8  
    More than 5 cells/field   6   0  
TNF   
    Yes   100   58  
    More than 10 cells/field   61   4  
    More than 20 cells/field
 
23
 
0
 



Pathologic GvHD, % n = 71

No evidence of GvHD, % n = 24
Edema   
    Yes   75   50  
    Moderate   44   8  
    Severe   15   0  
Eosinophils   
    Yes   52   4  
    More than 10/field   20   0  
    More than 20/field   4   0  
Neutrophils   
    Yes   55   13  
    More than 10/field   18   4  
    More than 20/field   6   4  
Lymphocytes   
    Yes   100   96  
    More than 20/field   76   17  
    More than 40/field   37   4  
Macrophages   
    Yes   89   71  
    More than 10/field   38   0  
    More than 20/field   13   0  
Apoptotic epithelial cells by TUNEL   
    Yes   99   8  
    More than 5/field   38   0  
    More than 10/field   8   0  
Apoptotic cells within the infiltrate by TUNEL   
    Yes   63   13  
    More than 5/field   11   4  
Fas expression within the cellular infiltrate   
    Yes   73   4  
    More than 5 cells/field   24   0  
TNFR-1   
    Yes   76   13  
    More than 5 cells/field   6   0  
TNFR-2   
    Yes   77   8  
    More than 5 cells/field   6   0  
TNF   
    Yes   100   58  
    More than 10 cells/field   61   4  
    More than 20 cells/field
 
23
 
0
 
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