Pathologic features on 95 duodenal biopsy specimens
. | Pathologic GvHD, % n = 71 . | No evidence of GvHD, % n = 24 . |
---|---|---|
Edema | ||
Yes | 75 | 50 |
Moderate | 44 | 8 |
Severe | 15 | 0 |
Eosinophils | ||
Yes | 52 | 4 |
More than 10/field | 20 | 0 |
More than 20/field | 4 | 0 |
Neutrophils | ||
Yes | 55 | 13 |
More than 10/field | 18 | 4 |
More than 20/field | 6 | 4 |
Lymphocytes | ||
Yes | 100 | 96 |
More than 20/field | 76 | 17 |
More than 40/field | 37 | 4 |
Macrophages | ||
Yes | 89 | 71 |
More than 10/field | 38 | 0 |
More than 20/field | 13 | 0 |
Apoptotic epithelial cells by TUNEL | ||
Yes | 99 | 8 |
More than 5/field | 38 | 0 |
More than 10/field | 8 | 0 |
Apoptotic cells within the infiltrate by TUNEL | ||
Yes | 63 | 13 |
More than 5/field | 11 | 4 |
Fas expression within the cellular infiltrate | ||
Yes | 73 | 4 |
More than 5 cells/field | 24 | 0 |
TNFR-1 | ||
Yes | 76 | 13 |
More than 5 cells/field | 6 | 0 |
TNFR-2 | ||
Yes | 77 | 8 |
More than 5 cells/field | 6 | 0 |
TNF | ||
Yes | 100 | 58 |
More than 10 cells/field | 61 | 4 |
More than 20 cells/field | 23 | 0 |
. | Pathologic GvHD, % n = 71 . | No evidence of GvHD, % n = 24 . |
---|---|---|
Edema | ||
Yes | 75 | 50 |
Moderate | 44 | 8 |
Severe | 15 | 0 |
Eosinophils | ||
Yes | 52 | 4 |
More than 10/field | 20 | 0 |
More than 20/field | 4 | 0 |
Neutrophils | ||
Yes | 55 | 13 |
More than 10/field | 18 | 4 |
More than 20/field | 6 | 4 |
Lymphocytes | ||
Yes | 100 | 96 |
More than 20/field | 76 | 17 |
More than 40/field | 37 | 4 |
Macrophages | ||
Yes | 89 | 71 |
More than 10/field | 38 | 0 |
More than 20/field | 13 | 0 |
Apoptotic epithelial cells by TUNEL | ||
Yes | 99 | 8 |
More than 5/field | 38 | 0 |
More than 10/field | 8 | 0 |
Apoptotic cells within the infiltrate by TUNEL | ||
Yes | 63 | 13 |
More than 5/field | 11 | 4 |
Fas expression within the cellular infiltrate | ||
Yes | 73 | 4 |
More than 5 cells/field | 24 | 0 |
TNFR-1 | ||
Yes | 76 | 13 |
More than 5 cells/field | 6 | 0 |
TNFR-2 | ||
Yes | 77 | 8 |
More than 5 cells/field | 6 | 0 |
TNF | ||
Yes | 100 | 58 |
More than 10 cells/field | 61 | 4 |
More than 20 cells/field | 23 | 0 |