Distribution of MTHFR genotypes in childhood ALL patients and controls
Variant . | MTHFR Genotype . | ALL cases, no. (%) . | Controls, no. (%) . | OR (95% CI) . | P . |
|---|---|---|---|---|---|
| C677T | CC | 112 (41.3) | 126 (42.0) | 1 (referent) | — |
| CT | 127 (47.0) | 128 (42.7) | 1.1 (0.8-1.6) | .6 | |
| TT | 31 (11.5) | 46 (15.3) | 0.8 (0.4-1.3) | .4 | |
| A1298T | AA | 151 (55.9) | 150 (50.0) | 1 (referent) | — |
| AC | 107 (39.6) | 119 (39.7) | 0.9 (0.6-1.3) | .5 | |
| CC | 12 (4.4) | 31 (10.3) | 0.4 (0.2-0.8) | < .01 |
Variant . | MTHFR Genotype . | ALL cases, no. (%) . | Controls, no. (%) . | OR (95% CI) . | P . |
|---|---|---|---|---|---|
| C677T | CC | 112 (41.3) | 126 (42.0) | 1 (referent) | — |
| CT | 127 (47.0) | 128 (42.7) | 1.1 (0.8-1.6) | .6 | |
| TT | 31 (11.5) | 46 (15.3) | 0.8 (0.4-1.3) | .4 | |
| A1298T | AA | 151 (55.9) | 150 (50.0) | 1 (referent) | — |
| AC | 107 (39.6) | 119 (39.7) | 0.9 (0.6-1.3) | .5 | |
| CC | 12 (4.4) | 31 (10.3) | 0.4 (0.2-0.8) | < .01 |
% indicates number of individuals with a given genotype/total number of individuals; OR, crude odds ratio; —, not applicable; and CI, confidence interval.