Table 2. Evaluating “new-onset”... | American Society of Hematology

Table 2.

Evaluating “new-onset” thrombocytopenia

Review bleeding history	ITP	Congenital
1. When was the onset of bleeding/bruising/petechiae?	Recent	Life-long
2. Have there been changes in general health? Any new medications?	Evaluate changes	No change
3. Has there been “excessive” bleeding after minor trauma, during menses, surgeries, childbirth?	No	Yes
4. Are there any family members with increased bleeding or thrombocytopenia?	No	Yes
5. Have there been previous normal platelet values? When?	Yes	No
6. What has been the response to treatment (steroids, IVIG, anti-D, splenectomy)?	Increased platelets (approximately 80%)	Variable/small effect
7. Response to platelet transfusions (if required)?	Poor response/short-lived	Good increment/normal survival

Review bleeding history	ITP	Congenital
1. When was the onset of bleeding/bruising/petechiae?	Recent	Life-long
2. Have there been changes in general health? Any new medications?	Evaluate changes	No change
3. Has there been “excessive” bleeding after minor trauma, during menses, surgeries, childbirth?	No	Yes
4. Are there any family members with increased bleeding or thrombocytopenia?	No	Yes
5. Have there been previous normal platelet values? When?	Yes	No
6. What has been the response to treatment (steroids, IVIG, anti-D, splenectomy)?	Increased platelets (approximately 80%)	Variable/small effect
7. Response to platelet transfusions (if required)?	Poor response/short-lived	Good increment/normal survival