Antibody responses to recombinant DBY and DBX measured by ELISA
Group . | Individuals tested . | Donor sex . | DBY positive, no. (%) . | DBX positive, no. (%) . |
|---|---|---|---|---|
| 1 | Male after HSCT | Female | 30/60 (50) | 2/60 (3) |
| 2 | Male after HSCT | Male | 2/39 (5) | 1/39 (3) |
| 3 | Male before HSCT | — | 3/48 (6) | 0/48 (0) |
| 4 | Female after HSCT | Female | 3/28 (11) | 1/28 (4) |
| 5 | Female after HSCT | Male | 4/23 (17) | 3/23 (13) |
| 6 | Female before HSCT | — | 6/24 (25) | 0/24 (0) |
| 7 | Healthy male | — | 0/30 (0) | 0/30 (0) |
| 8 | Healthy female | — | 6/35 (17) | 0/35 (0) |
Group . | Individuals tested . | Donor sex . | DBY positive, no. (%) . | DBX positive, no. (%) . |
|---|---|---|---|---|
| 1 | Male after HSCT | Female | 30/60 (50) | 2/60 (3) |
| 2 | Male after HSCT | Male | 2/39 (5) | 1/39 (3) |
| 3 | Male before HSCT | — | 3/48 (6) | 0/48 (0) |
| 4 | Female after HSCT | Female | 3/28 (11) | 1/28 (4) |
| 5 | Female after HSCT | Male | 4/23 (17) | 3/23 (13) |
| 6 | Female before HSCT | — | 6/24 (25) | 0/24 (0) |
| 7 | Healthy male | — | 0/30 (0) | 0/30 (0) |
| 8 | Healthy female | — | 6/35 (17) | 0/35 (0) |
With the 2-sided McNemar test, P < .001 for the comparison of DBY versus DBX in male patients after HSCT with female donors; P = .03 for the comparison of DBY versus DBX in healthy females. For DBY comparisons by 2-sided Fisher exact test, P < .001 for group 1 versus 2, group 1 versus 4, group 1 versus 7; P = .64 for group 2 versus 4; and P = .03 for group 7 versus 8.