Clinical and cellular features of TP53-mutant B-CLL tumors analyzed in microarray experiments
Tumor . | TP53 mutation . | p53 induction . | VH status . | Clinical course . |
|---|---|---|---|---|
| TP53-1 | 472C > G (158R > G) and LOH across TP53 | D | Unmutated | P |
| TP53-2 | 844C > T (282R > W) and LOH across TP53 | D | Unmutated | P |
| TP53-3 | 1207ins133bp | D | Unmutated | P |
| TP53-4 | 210ins2bp | D | Unmutated | P |
| TP53-5 | 701A > G (234Y > C) and LOH across TP53 | D | Mutated | P |
Tumor . | TP53 mutation . | p53 induction . | VH status . | Clinical course . |
|---|---|---|---|---|
| TP53-1 | 472C > G (158R > G) and LOH across TP53 | D | Unmutated | P |
| TP53-2 | 844C > T (282R > W) and LOH across TP53 | D | Unmutated | P |
| TP53-3 | 1207ins133bp | D | Unmutated | P |
| TP53-4 | 210ins2bp | D | Unmutated | P |
| TP53-5 | 701A > G (234Y > C) and LOH across TP53 | D | Mutated | P |
D indicates defective; P, progressive.