Immunohistochemical stain results, TMA subclassification, IPI scores, and their effect on (OS) and EFS by univariate analysis
. | No. (%) . | 5-y OS, % (95% CI) . | P* . | 5-y EFS, % (95% CI) . | P* . |
|---|---|---|---|---|---|
| CD10 | |||||
| Negative | 110 (72) | 44 (34-53) | .019 | 47 (37-57) | .89 |
| Positive | 42 (28) | 74 (60-87) | 51 (35-68) | ||
| Bcl-6 | |||||
| Negative | 67 (44) | 30 (18-42) | < .001 | 35 (22-49) | .013 |
| Positive | 85 (56) | 69 (59-79) | 57 (46-68) | ||
| MUM1 | |||||
| Negative | 80 (53) | 66 (55-76) | .009 | 62 (51-74) | .003 |
| Positive | 71 (47) | 36 (24-48) | 31 (19-43) | ||
| Cyclin D2 | |||||
| Negative | 133 (87) | 58 (45-71) | < .001 | 54 (44-63) | < .001 |
| Positive | 19 (13) | 11 (0-26) | 7 (0-20) | ||
| Bcl-2 | |||||
| Negative | 76 (50) | 55 (43-66) | .17 | 54 (42-67) | .17 |
| Positive | 76 (50) | 50 (38-61) | 42 (30-55) | ||
| FOXP1 | |||||
| Negative | 57 (39) | 58 (45-71) | .29 | 52 (38-66) | .25 |
| Positive | 90 (61) | 50 (39-61) | 48 (36-59) | ||
| TMA | |||||
| GCB | 64 (42) | 76 (66-87) | < .001 | 63 (50-76) | .007 |
| Non-GCB | 88 (58) | 34 (24-45) | 36 (25-47) | ||
| IPI score | |||||
| 0-2 | 84 (66) | 68 (58-78) | < .001 | 65 (54-76) | < .001 |
| 3-5 | 44 (34) | 31 (17-45) | 23 (9-37) |
. | No. (%) . | 5-y OS, % (95% CI) . | P* . | 5-y EFS, % (95% CI) . | P* . |
|---|---|---|---|---|---|
| CD10 | |||||
| Negative | 110 (72) | 44 (34-53) | .019 | 47 (37-57) | .89 |
| Positive | 42 (28) | 74 (60-87) | 51 (35-68) | ||
| Bcl-6 | |||||
| Negative | 67 (44) | 30 (18-42) | < .001 | 35 (22-49) | .013 |
| Positive | 85 (56) | 69 (59-79) | 57 (46-68) | ||
| MUM1 | |||||
| Negative | 80 (53) | 66 (55-76) | .009 | 62 (51-74) | .003 |
| Positive | 71 (47) | 36 (24-48) | 31 (19-43) | ||
| Cyclin D2 | |||||
| Negative | 133 (87) | 58 (45-71) | < .001 | 54 (44-63) | < .001 |
| Positive | 19 (13) | 11 (0-26) | 7 (0-20) | ||
| Bcl-2 | |||||
| Negative | 76 (50) | 55 (43-66) | .17 | 54 (42-67) | .17 |
| Positive | 76 (50) | 50 (38-61) | 42 (30-55) | ||
| FOXP1 | |||||
| Negative | 57 (39) | 58 (45-71) | .29 | 52 (38-66) | .25 |
| Positive | 90 (61) | 50 (39-61) | 48 (36-59) | ||
| TMA | |||||
| GCB | 64 (42) | 76 (66-87) | < .001 | 63 (50-76) | .007 |
| Non-GCB | 88 (58) | 34 (24-45) | 36 (25-47) | ||
| IPI score | |||||
| 0-2 | 84 (66) | 68 (58-78) | < .001 | 65 (54-76) | < .001 |
| 3-5 | 44 (34) | 31 (17-45) | 23 (9-37) |
P values were determined by comparing survival distributions using the log-rank test.