Clinical and biologic characteristics at diagnosis
Variables . | No. of patients (%) . | Mean (± SD) . | Median (range) . |
|---|---|---|---|
| Age, y | 48.00 (22-81) | ||
| Sex | |||
| Male | 20 (67) | ||
| Female | 10 (33) | ||
| Sokal risk group | |||
| Low | 11 (37) | ||
| Intermediate | 14 (47) | ||
| High | 5 (16) | ||
| Euro risk group | |||
| Low | 17 (57) | ||
| Intermediate | 12 (40) | ||
| High | 1 (3) | ||
| Spleen size, cm below costal margin | |||
| Normal | 17 (57) | 5.85 (± 3.70) | 6.00 (1-12) |
| Abnormal | 13 (43) | ||
| Hemoglobin, g/100 mL | 30 | 12.26 (± 2.18) | 12.85 (9.10-16.20) |
| Platelet count, × 109/L | 30 | 480.20 (± 321.97) | 433.00 (96.00-1499.00) |
| WBC count, × 109/L | 30 | 159.76 (± 238.43) | 66.05 (6.90-470.00) |
| Immature cells | |||
| Fewer than 5 | 4 (13) | — | — |
| 5 or more | 26 (87) | 27.80 (± 14.32) | 24.00 (6.00-58.00) |
| Blood blasts | |||
| 0% | 15 (50) | — | — |
| More than 0% | 15 (50) | 3.73 (± 3.04) | 3.00 (1.00-11.00) |
| Marrow blasts | |||
| 0% | 3 (10) | — | — |
| More than 0% | 17 (90) | 2.35 (± 1.63) | 2.00 (1.00-5.00) |
| Chromosomal anomalies | 6 (20) | ||
| Trisomy 8 | 1 (3) | ||
| Variant translocation involving chromosomes 7 and 20 | 2 (7) | ||
| Additional translocation (t9;14) | 1 (3) | ||
| Klinefelter syndrome | 1 (3) | ||
| Marked chromosome | 1 (3) |
Variables . | No. of patients (%) . | Mean (± SD) . | Median (range) . |
|---|---|---|---|
| Age, y | 48.00 (22-81) | ||
| Sex | |||
| Male | 20 (67) | ||
| Female | 10 (33) | ||
| Sokal risk group | |||
| Low | 11 (37) | ||
| Intermediate | 14 (47) | ||
| High | 5 (16) | ||
| Euro risk group | |||
| Low | 17 (57) | ||
| Intermediate | 12 (40) | ||
| High | 1 (3) | ||
| Spleen size, cm below costal margin | |||
| Normal | 17 (57) | 5.85 (± 3.70) | 6.00 (1-12) |
| Abnormal | 13 (43) | ||
| Hemoglobin, g/100 mL | 30 | 12.26 (± 2.18) | 12.85 (9.10-16.20) |
| Platelet count, × 109/L | 30 | 480.20 (± 321.97) | 433.00 (96.00-1499.00) |
| WBC count, × 109/L | 30 | 159.76 (± 238.43) | 66.05 (6.90-470.00) |
| Immature cells | |||
| Fewer than 5 | 4 (13) | — | — |
| 5 or more | 26 (87) | 27.80 (± 14.32) | 24.00 (6.00-58.00) |
| Blood blasts | |||
| 0% | 15 (50) | — | — |
| More than 0% | 15 (50) | 3.73 (± 3.04) | 3.00 (1.00-11.00) |
| Marrow blasts | |||
| 0% | 3 (10) | — | — |
| More than 0% | 17 (90) | 2.35 (± 1.63) | 2.00 (1.00-5.00) |
| Chromosomal anomalies | 6 (20) | ||
| Trisomy 8 | 1 (3) | ||
| Variant translocation involving chromosomes 7 and 20 | 2 (7) | ||
| Additional translocation (t9;14) | 1 (3) | ||
| Klinefelter syndrome | 1 (3) | ||
| Marked chromosome | 1 (3) |