Growth of parental PEL cells and their EBV convertants in SCID mice
Cell line . | Virus . | Dose . | Route . | No. of mice with tumors/total inoculated . |
|---|---|---|---|---|
| BC-3 | HHV-8 | 10 × 106 | SC | 0/9 |
| BC-3 GFP EBV cl-6 | HHV-8 + EBV | 10 × 106 | SC | 8/9 |
| BC-3 GFPEBV cl-10 | HHV-8 + EBV | 10 × 106 | SC | 1/6 |
| CRO-AP/6 | HHV-8 | 1 × 106 | SC | 0/6 |
| 3 × 106 | SC | 0/6 | ||
| 10 × 106 | SC | 6/6 | ||
| CRO-AP/6 GFPEBV cl-1 | HHV-8 + EBV | 1 × 106 | SC | 6/6 |
| 3 × 106 | SC | 6/6 | ||
| 10 × 106 | SC | 6/6 |
Cell line . | Virus . | Dose . | Route . | No. of mice with tumors/total inoculated . |
|---|---|---|---|---|
| BC-3 | HHV-8 | 10 × 106 | SC | 0/9 |
| BC-3 GFP EBV cl-6 | HHV-8 + EBV | 10 × 106 | SC | 8/9 |
| BC-3 GFPEBV cl-10 | HHV-8 + EBV | 10 × 106 | SC | 1/6 |
| CRO-AP/6 | HHV-8 | 1 × 106 | SC | 0/6 |
| 3 × 106 | SC | 0/6 | ||
| 10 × 106 | SC | 6/6 | ||
| CRO-AP/6 GFPEBV cl-1 | HHV-8 + EBV | 1 × 106 | SC | 6/6 |
| 3 × 106 | SC | 6/6 | ||
| 10 × 106 | SC | 6/6 |
SCID mice, aged 4 to 5 weeks, were inoculated with indicated tumor cells. SC indicates subcutaneous.