Table 5.

Characteristics of the patients having developed a cardiac event or other life-threatening or fatal event in the H90-NM trial

Arm
Sex, age, y, and clinical stage at HD diagnosis
Time from completion of therapy to event, mo
Event developed in an irradiated area
Type of event
Survival from event, mo
Cardiac events      
    A   F, 26, IIIA   66   Yes   Myocardial infarction   63  
    A   M, 34, IIB   31   No   Myocardial infarction   107  
    A   F, 35, IIA   19   Yes   Myocardial infarction   76  
    A   M, 36, IIA   35   Yes   Myocardial infarction   81  
    A   M, 36, IIA   60   No   Myocardial infarction   28  
    A   M, 37, IA   94   Yes   Myocardial infarction   0* 
    A   F, 40, IIA   73   Yes   Myocardial infarction   2  
    +A   M, 57, IIA   42   Yes   Myocardial infarction   55  
    E   M, 19, IIIA   104   Yes   Myocardial infarction   39  
    E   F, 23, IIB†  4   Yes   Congestive heart failure   96  
    E   M, 36, IIB†  99   Yes   Myocardial infarction   14  
    E   M, 42, IIA   75   Yes   Angina pectoris   37  
    E   M, 45, IIA†  47   Yes   Angina pectoris   59  
    E   M, 46, IIIB   46   Yes   Myocardial infarction   19‡ 
    E   M, 60, IIB   74   Yes   Dysrhythmia   62  
    E   M, 65, IIIB†  31   Yes   Myocardial infarction   0* 
    E   M, 65, IIA   90   Yes   Angina pectoris   15* 
    E   F, 65, IA   2   Yes   Myocardial infarction   88  
Other events      
    A   M, 45, IA†  15   No   Stroke   0* 
    A   M, 49, IIIB   36   Yes   Postoperative sepsis   1* 
    E
 		 F, 58, IIIB
 		 8
 		 No
 		 Multifocal leukoencephalitis
 		 1*
 
Arm
Sex, age, y, and clinical stage at HD diagnosis
Time from completion of therapy to event, mo
Event developed in an irradiated area
Type of event
Survival from event, mo
Cardiac events      
    A   F, 26, IIIA   66   Yes   Myocardial infarction   63  
    A   M, 34, IIB   31   No   Myocardial infarction   107  
    A   F, 35, IIA   19   Yes   Myocardial infarction   76  
    A   M, 36, IIA   35   Yes   Myocardial infarction   81  
    A   M, 36, IIA   60   No   Myocardial infarction   28  
    A   M, 37, IA   94   Yes   Myocardial infarction   0* 
    A   F, 40, IIA   73   Yes   Myocardial infarction   2  
    +A   M, 57, IIA   42   Yes   Myocardial infarction   55  
    E   M, 19, IIIA   104   Yes   Myocardial infarction   39  
    E   F, 23, IIB†  4   Yes   Congestive heart failure   96  
    E   M, 36, IIB†  99   Yes   Myocardial infarction   14  
    E   M, 42, IIA   75   Yes   Angina pectoris   37  
    E   M, 45, IIA†  47   Yes   Angina pectoris   59  
    E   M, 46, IIIB   46   Yes   Myocardial infarction   19‡ 
    E   M, 60, IIB   74   Yes   Dysrhythmia   62  
    E   M, 65, IIIB†  31   Yes   Myocardial infarction   0* 
    E   M, 65, IIA   90   Yes   Angina pectoris   15* 
    E   F, 65, IA   2   Yes   Myocardial infarction   88  
Other events      
    A   M, 45, IA†  15   No   Stroke   0* 
    A   M, 49, IIIB   36   Yes   Postoperative sepsis   1* 
    E
 		 F, 58, IIIB
 		 8
 		 No
 		 Multifocal leukoencephalitis
 		 1*
 
*

Patient is deceased.

†

Patient has received a second-line anthracycline-based chemotherapy.

‡

Patient died of larynx cancer (see Table 4).

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