Initial characteristics of the 386 adult patients with early/intermediate Hodgkin disease included in the H90-NM trial
. | All . | Arm E (EBVMm-RT) . | Arm A (ABVDm-RT) . |
|---|---|---|---|
| Patients | 386 | 186 | 200 |
| Sex | |||
| Male | 206 | 90 | 116 |
| Female | 180 | 96 | 84 |
| Age | |||
| Younger than 40 years | 279 | 132 | 147 |
| 40 years and older | 107 | 54 | 53 |
| Histology | |||
| Nodular sclerosis | 260 | 132 | 128 |
| Other subtypes | 126 | 54 | 72 |
| Clinical stages | |||
| IA | 81 | 33 | 48 |
| IIA | 195 | 95 | 100 |
| IIIA | 25 | 12 | 13 |
| IB-IIB | 65 | 36 | 29 |
| IIIB | 20 | 10 | 10 |
| Clinical presentation | |||
| Supradiaphragmatic CS I/II: | |||
| With MMR less than 0.33: | |||
| No symptoms | 211 | 96 | 115 |
| Symptoms | 46 | 26 | 20 |
| MMR 0.33 and greater and less than 0.45 | 64 | 34 | 30 |
| Infradiaphragmatic CS I/II | 20 | 8 | 12 |
| CS III | 45 | 22 | 23 |
| Contiguous extra nodal involvement | |||
| No | 371 | 179 | 192 |
| Yes | 15 | 7 | 8 |
. | All . | Arm E (EBVMm-RT) . | Arm A (ABVDm-RT) . |
|---|---|---|---|
| Patients | 386 | 186 | 200 |
| Sex | |||
| Male | 206 | 90 | 116 |
| Female | 180 | 96 | 84 |
| Age | |||
| Younger than 40 years | 279 | 132 | 147 |
| 40 years and older | 107 | 54 | 53 |
| Histology | |||
| Nodular sclerosis | 260 | 132 | 128 |
| Other subtypes | 126 | 54 | 72 |
| Clinical stages | |||
| IA | 81 | 33 | 48 |
| IIA | 195 | 95 | 100 |
| IIIA | 25 | 12 | 13 |
| IB-IIB | 65 | 36 | 29 |
| IIIB | 20 | 10 | 10 |
| Clinical presentation | |||
| Supradiaphragmatic CS I/II: | |||
| With MMR less than 0.33: | |||
| No symptoms | 211 | 96 | 115 |
| Symptoms | 46 | 26 | 20 |
| MMR 0.33 and greater and less than 0.45 | 64 | 34 | 30 |
| Infradiaphragmatic CS I/II | 20 | 8 | 12 |
| CS III | 45 | 22 | 23 |
| Contiguous extra nodal involvement | |||
| No | 371 | 179 | 192 |
| Yes | 15 | 7 | 8 |
MMR indicates mediastinal mass ratio (defined in “Patients and methods”).