Table 2.

Initial characteristics of the 386 adult patients with early/intermediate Hodgkin disease included in the H90-NM trial




All

Arm E (EBVMm-RT)

Arm A (ABVDm-RT)
Patients   386   186   200  
Sex    
    Male   206   90   116  
    Female   180   96   84  
Age    
    Younger than 40 years   279   132   147  
    40 years and older   107   54   53  
Histology    
    Nodular sclerosis   260   132   128  
    Other subtypes   126   54   72  
Clinical stages    
    IA   81   33   48  
    IIA   195   95   100  
    IIIA   25   12   13  
IB-IIB   65   36   29  
    IIIB   20   10   10  
Clinical presentation    
    Supradiaphragmatic CS I/II:     
        With MMR less than 0.33:     
            No symptoms   211   96   115  
            Symptoms   46   26   20  
        MMR 0.33 and greater and less than 0.45   64   34   30  
    Infradiaphragmatic CS I/II   20   8   12  
    CS III   45   22   23  
Contiguous extra nodal involvement    
    No   371   179   192  
Yes
 
15
 
7
 
8
 



All

Arm E (EBVMm-RT)

Arm A (ABVDm-RT)
Patients   386   186   200  
Sex    
    Male   206   90   116  
    Female   180   96   84  
Age    
    Younger than 40 years   279   132   147  
    40 years and older   107   54   53  
Histology    
    Nodular sclerosis   260   132   128  
    Other subtypes   126   54   72  
Clinical stages    
    IA   81   33   48  
    IIA   195   95   100  
    IIIA   25   12   13  
IB-IIB   65   36   29  
    IIIB   20   10   10  
Clinical presentation    
    Supradiaphragmatic CS I/II:     
        With MMR less than 0.33:     
            No symptoms   211   96   115  
            Symptoms   46   26   20  
        MMR 0.33 and greater and less than 0.45   64   34   30  
    Infradiaphragmatic CS I/II   20   8   12  
    CS III   45   22   23  
Contiguous extra nodal involvement    
    No   371   179   192  
Yes
 
15
 
7
 
8
 

MMR indicates mediastinal mass ratio (defined in “Patients and methods”).

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