Patient characteristics of unrelated donor transplantations (n = 1108)
Characteristic . | Donor CMV-seropositive (%) N = 566 . | Donor CMV-seronegative (%) N = 542 . | P* . |
|---|---|---|---|
| Year of transplantation | .86 | ||
| 1992 and before | 61 (10.8) | 54 (10.0) | |
| 1993-1996 | 208 (36.7) | 204 (37.6) | |
| 1997 and after | 297 (52.5) | 284 (52.4) | |
| Age, y | 26 (15) | 27 (15) | .27 |
| Patient sex | .56 | ||
| Male | 310 (54.8) | 308 (56.8) | |
| Female | 256 (45.2) | 234 (43.2) | |
| Stem cell source | .05 | ||
| Bone marrow | 494 (87.3) | 445 (82.1) | |
| Peripheral blood | 35 (6.2) | 45 (8.3) | |
| Other | 37 (6.5) | 52 (9.6) | |
| Diagnosis | .21 | ||
| Acute leukemia | 261 (46.1) | 268 (49.4) | |
| CML | 183 (32.3) | 149 (27.5) | |
| Other | 122 (22.6) | 125 (33.1) | |
| Stage | .17 | ||
| Early stage | 271 (66.4) | 241 (61.8) | |
| Advanced stage | 137 (33.6) | 149 (38.2) | |
| HLA A, B, DRβ1 | .10 | ||
| Match | 474 (83.7) | 433 (79.9) | |
| Mismatch | 92 (16.3) | 109 (21.1) | |
| T-cell depletion and ATG | .91 | ||
| T-cell depletion | 148 (26.2) | 147 (27.1) | |
| ATG | 57 (11.1) | 59 (10.9) | |
| Neither | 294 (51.9) | 281 (51.8) | |
| Missing data | 67 (11.8) | 55 (10.2) |
Characteristic . | Donor CMV-seropositive (%) N = 566 . | Donor CMV-seronegative (%) N = 542 . | P* . |
|---|---|---|---|
| Year of transplantation | .86 | ||
| 1992 and before | 61 (10.8) | 54 (10.0) | |
| 1993-1996 | 208 (36.7) | 204 (37.6) | |
| 1997 and after | 297 (52.5) | 284 (52.4) | |
| Age, y | 26 (15) | 27 (15) | .27 |
| Patient sex | .56 | ||
| Male | 310 (54.8) | 308 (56.8) | |
| Female | 256 (45.2) | 234 (43.2) | |
| Stem cell source | .05 | ||
| Bone marrow | 494 (87.3) | 445 (82.1) | |
| Peripheral blood | 35 (6.2) | 45 (8.3) | |
| Other | 37 (6.5) | 52 (9.6) | |
| Diagnosis | .21 | ||
| Acute leukemia | 261 (46.1) | 268 (49.4) | |
| CML | 183 (32.3) | 149 (27.5) | |
| Other | 122 (22.6) | 125 (33.1) | |
| Stage | .17 | ||
| Early stage | 271 (66.4) | 241 (61.8) | |
| Advanced stage | 137 (33.6) | 149 (38.2) | |
| HLA A, B, DRβ1 | .10 | ||
| Match | 474 (83.7) | 433 (79.9) | |
| Mismatch | 92 (16.3) | 109 (21.1) | |
| T-cell depletion and ATG | .91 | ||
| T-cell depletion | 148 (26.2) | 147 (27.1) | |
| ATG | 57 (11.1) | 59 (10.9) | |
| Neither | 294 (51.9) | 281 (51.8) | |
| Missing data | 67 (11.8) | 55 (10.2) |
Early stage indicates first complete remission, second complete remission, or first chronic stage.
Chi-square test was used for categorical variables; if ordered, a trend version was used; t test was used for continuous variables.