Patient characteristics of HLA-identical sibling transplantations (n = 5905)
Characteristic . | Donor CMV-seropositive (%) N = 4451 . | Donor CMV-seronegative (%) N = 1454 . | P* . |
|---|---|---|---|
| Year of transplantation | .41 | ||
| 1992 or before | 1697 (38.1) | 581 (40.0) | |
| 1993-1996 | 1506 (33.8) | 468 (32.2) | |
| 1997 and after | 1248 (28.1) | 405 (27.8) | |
| Age, y | 32 (14) | 30 (14) | <.01 |
| Patient sex | .31 | ||
| Male | 2536 (57.0) | 805 (55.4) | |
| Female | 1915 (43.0) | 649 (44.6) | |
| Stem cell source | <.01 | ||
| Bone marrow | 3562 (80.0) | 1185 (81.5) | |
| Peripheral blood | 731 (16.4) | 187 (12.9) | |
| Other | 158 (3.6) | 82 (5.6) | |
| Diagnosis | <.01 | ||
| Acute leukemia | 2207 (49.6) | 803 (55.2) | |
| CML | 1135 (25.5) | 203 (14.0) | |
| Other | 1109 (24.9) | 398 (27.4) | |
| Stage | .44 | ||
| Early stage | 2479 (77.7) | 789 (78.9) | |
| Advanced stage | 710 (23.3) | 211 (21.1) | |
| T-cell depletion and ATG | <.01 | ||
| T-cell depletion | 721 (16.2) | 214 (14.7) | |
| ATG | 48 (1.0) | 10 (0.7) | |
| Neither | 2470 (55.5) | 940 (64.6) | |
| Missing data | 1212 (27.3) | 290 (20.0) |
Characteristic . | Donor CMV-seropositive (%) N = 4451 . | Donor CMV-seronegative (%) N = 1454 . | P* . |
|---|---|---|---|
| Year of transplantation | .41 | ||
| 1992 or before | 1697 (38.1) | 581 (40.0) | |
| 1993-1996 | 1506 (33.8) | 468 (32.2) | |
| 1997 and after | 1248 (28.1) | 405 (27.8) | |
| Age, y | 32 (14) | 30 (14) | <.01 |
| Patient sex | .31 | ||
| Male | 2536 (57.0) | 805 (55.4) | |
| Female | 1915 (43.0) | 649 (44.6) | |
| Stem cell source | <.01 | ||
| Bone marrow | 3562 (80.0) | 1185 (81.5) | |
| Peripheral blood | 731 (16.4) | 187 (12.9) | |
| Other | 158 (3.6) | 82 (5.6) | |
| Diagnosis | <.01 | ||
| Acute leukemia | 2207 (49.6) | 803 (55.2) | |
| CML | 1135 (25.5) | 203 (14.0) | |
| Other | 1109 (24.9) | 398 (27.4) | |
| Stage | .44 | ||
| Early stage | 2479 (77.7) | 789 (78.9) | |
| Advanced stage | 710 (23.3) | 211 (21.1) | |
| T-cell depletion and ATG | <.01 | ||
| T-cell depletion | 721 (16.2) | 214 (14.7) | |
| ATG | 48 (1.0) | 10 (0.7) | |
| Neither | 2470 (55.5) | 940 (64.6) | |
| Missing data | 1212 (27.3) | 290 (20.0) |
Early stage indicates first complete remission, second complete remission, or first chronic stage.
Chi-square test is used for categorical variables; if ordered, a trend version was used; t test was used for continuous variables.