Frequency of human cells in the bone marrow of SCID mice reconstituted with human CD34+HPCs and challenged or not in vivo with live flu virus
Subsets of human cells . | No virus, n = 3 . | Flu virus, n = 4 . |
|---|---|---|
| CD45 | 52.4 ± 17.6 | 21.6 ± 12.3 (P < .05) |
| CD19 | 19.2 ± 5.8 | 10.2 ± 6 (P = .1) |
| CD14 | 19.5 ± 6.8 | 5.6 ± 3 (P < .05) |
| CD4 | 22 ± 6.5 | 7.9 ± 3.9 (P < .05) |
| CD11c+DC | 12.3 ± 5.8 | 4.4 ± 2.9 (P = .06) |
| CD123+DC | 5.6 ± 3.1 | 2.6 ± 1.7 (P = .1) |
Subsets of human cells . | No virus, n = 3 . | Flu virus, n = 4 . |
|---|---|---|
| CD45 | 52.4 ± 17.6 | 21.6 ± 12.3 (P < .05) |
| CD19 | 19.2 ± 5.8 | 10.2 ± 6 (P = .1) |
| CD14 | 19.5 ± 6.8 | 5.6 ± 3 (P < .05) |
| CD4 | 22 ± 6.5 | 7.9 ± 3.9 (P < .05) |
| CD11c+DC | 12.3 ± 5.8 | 4.4 ± 2.9 (P = .06) |
| CD123+DC | 5.6 ± 3.1 | 2.6 ± 1.7 (P = .1) |
Experiment 4 in Table 1. B cells (CD19+), monocytes (CD14+), and CD4+ cells (DCs) were identified as a fraction of human CD45+ cells. CD11c+ mDCs and CD123+ pDCs were identified as a fraction of total bone marrow. Average ± standard deviation.