Table 2. Frequency of human cells in... | American Society of Hematology

Table 2.

Frequency of human cells in reconstituted NOD/SCID mice bone marrow; B cells (CD19⁺), monocytes (CD14⁺), and cells labeling with CD3 are represented as a fraction of human CD45⁺ cells

		Bone marrow
Experiment	HPCs source	% CD45⁺	% CD19*	% CD14*	% CD3*	% CD45+	% CD19*
						*17 ± 26*	*87 ± 9*
*1, n = 5*	*MPB, FL*	*31 ± 31*	*62 ± 34*	ND	ND	*n = 4*	*n = 4*
2, n = 4	MPB	59 ± 9	63 ± 14	9 ± 4.6	2 ± 0.4	ND	ND
*3, n = 6*	*CB/FL*	*34 ± 8*	*75 ± 10*	*11 ± 4*	*1.5 ± 0.6*	ND	ND
4, n = 3†	FL	38 ± 13	37 ± 1.7	37 ± 2.6	2 ± 0.6	ND	ND
*5, n = 4*	*MPB*	*9 ± 6.5*	*68 ± 6*	*28 ± 5*	*4.5 ± 2*	*2 ± 2*	*69 ± 10*
6, n = 2	CB	60	ND	ND	2.8	ND	ND

		Bone marrow
Experiment	HPCs source	% CD45⁺	% CD19*	% CD14*	% CD3*	% CD45+	% CD19*
						*17 ± 26*	*87 ± 9*
*1, n = 5*	*MPB, FL*	*31 ± 31*	*62 ± 34*	ND	ND	*n = 4*	*n = 4*
2, n = 4	MPB	59 ± 9	63 ± 14	9 ± 4.6	2 ± 0.4	ND	ND
*3, n = 6*	*CB/FL*	*34 ± 8*	*75 ± 10*	*11 ± 4*	*1.5 ± 0.6*	ND	ND
4, n = 3†	FL	38 ± 13	37 ± 1.7	37 ± 2.6	2 ± 0.6	ND	ND
*5, n = 4*	*MPB*	*9 ± 6.5*	*68 ± 6*	*28 ± 5*	*4.5 ± 2*	*2 ± 2*	*69 ± 10*
6, n = 2	CB	60	ND	ND	2.8	ND	ND

Average ± standard deviation.

MPB indicates mobilized peripheral blood HPCs (G-CSF); CB, cord blood HPCs; FL, fetal liver HPCs; and ND, not done.

Percentage positive in the gate for CD45⁺ cells.

†

Only the data from mice that were reconstituted but did not receive influenza virus are given.

View Large

This Feature Is Available To Subscribers Only