Table 1. Frequency of engraftment... | American Society of Hematology

Table 1.

Frequency of engraftment

Experiment	Age of mice (weeks)	Source of CD34⁺ HPCs	Time reconstituted after transplantation (weeks)	Reconstitution as human CD45⁺ cells in bone marrow	Skin*	Lung*	Spleen*	Liver*
1	17	*MPB/CB/FL*	8	*5/13*	*2/2*	*2/2*	*4/13*	*2/2*
2	8-12	MPB	14	4/4	0/4	4/4	4/4	4/4
3	*8-12*	*CB/FL*	14	*6/6*	*2/4*	*3/4*	*4/4*	*4/4*
4	21	FL	16	7/7	1/1	1/1	6/6	ND
5	13	*MPB*	*15-16*	*4/7*	ND	ND	ND	ND
6	12	CB	19	4/4	ND	ND	4/4	ND
7	8	*MPB†*	11	*6/6*	ND	ND	*6/6*	ND

Experiment	Age of mice (weeks)	Source of CD34⁺ HPCs	Time reconstituted after transplantation (weeks)	Reconstitution as human CD45⁺ cells in bone marrow	Skin*	Lung*	Spleen*	Liver*
1	17	*MPB/CB/FL*	8	*5/13*	*2/2*	*2/2*	*4/13*	*2/2*
2	8-12	MPB	14	4/4	0/4	4/4	4/4	4/4
3	*8-12*	*CB/FL*	14	*6/6*	*2/4*	*3/4*	*4/4*	*4/4*
4	21	FL	16	7/7	1/1	1/1	6/6	ND
5	13	*MPB*	*15-16*	*4/7*	ND	ND	ND	ND
6	12	CB	19	4/4	ND	ND	4/4	ND
7	8	*MPB†*	11	*6/6*	ND	ND	*6/6*	ND

MPB indicates mobilized peripheral blood HPCs (G-CSF); CB, cord blood HPCs; FL, fetal liver HPCs; and ND, not done.

Number of mice displaying human cells/number of tested mice.

1.5 × 10⁶ HPCs/injection/mouse.