Liver toxicity criteria
Liver criteria . | Grade 0 . | Grade 1 . | Grade 2 . | Grade 3 . | Grade 4 . |
|---|---|---|---|---|---|
| Bilirubin | WNL | WNL | ULN to 1.5 × ULN | > 1.5-3.0 × ULN | > 3.0 × ULN |
| AST | WNL | ULN to 2.5 × ULN | > 2.5-5.0 × ULN | 5.0-20.0 × ULN | > 20.0 × ULN |
| ALT | WNL | ULN to 2.5 × ULN | > 2.5-5.0 × ULN | 5.0-20.0 × ULN | > 20.0 × ULN |
Liver criteria . | Grade 0 . | Grade 1 . | Grade 2 . | Grade 3 . | Grade 4 . |
|---|---|---|---|---|---|
| Bilirubin | WNL | WNL | ULN to 1.5 × ULN | > 1.5-3.0 × ULN | > 3.0 × ULN |
| AST | WNL | ULN to 2.5 × ULN | > 2.5-5.0 × ULN | 5.0-20.0 × ULN | > 20.0 × ULN |
| ALT | WNL | ULN to 2.5 × ULN | > 2.5-5.0 × ULN | 5.0-20.0 × ULN | > 20.0 × ULN |
WNL indicates within normal limits; ULN, upper limit of normal.