Table 6.

Outcome of consolidation cohorts


Cohort

Treatment

No.

ANC to 1.0 × 109/L, d median (range)

Platelets to 100 × 109/L, d median (range)

Grade 3 or 4 hepatotoxicity

Deaths
7   MACE and 3 mg/m2 GO   18   27.5 (17-55)   45 (19-70)   3   2  
8   HidAC and 3 mg/m2 GO   13   28.5 (21-51)   45 (21-59)   0   0  
9
 
Course 1 with 3 mg/m2 GO and Course 3 (either MACE or HidAC) with 3 mg/m2 GO
 
23
 
28 (17-55)
 
44.5 (19-70)
 
1
 
0
 

Cohort

Treatment

No.

ANC to 1.0 × 109/L, d median (range)

Platelets to 100 × 109/L, d median (range)

Grade 3 or 4 hepatotoxicity

Deaths
7   MACE and 3 mg/m2 GO   18   27.5 (17-55)   45 (19-70)   3   2  
8   HidAC and 3 mg/m2 GO   13   28.5 (21-51)   45 (21-59)   0   0  
9
 
Course 1 with 3 mg/m2 GO and Course 3 (either MACE or HidAC) with 3 mg/m2 GO
 
23
 
28 (17-55)
 
44.5 (19-70)
 
1
 
0
 
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