Clinical benefits from Fanconi anemia subtyping
1 | Confirms FA diagnosis |
| 2 | Identifies FA-D1/BRCA2 families |
| 3 | Distinguishes FA from other FA-related chromosome breakage disorders (NBS, AT) |
| 4 | Required for FA mutation carrier detection |
| 5 | Required for enrollment in FA-A and FA-C gene therapy trials |
| 6 | Identifies new variant forms of FA |
1 | Confirms FA diagnosis |
| 2 | Identifies FA-D1/BRCA2 families |
| 3 | Distinguishes FA from other FA-related chromosome breakage disorders (NBS, AT) |
| 4 | Required for FA mutation carrier detection |
| 5 | Required for enrollment in FA-A and FA-C gene therapy trials |
| 6 | Identifies new variant forms of FA |
AT indicates ataxia telangiectasia.