Clonogenic ability of c-Kit+/CD31high/Ly-6C- cells
. | Bone marrow cells, % . | c-Kit+/CD31high/Ly-6C-, % . |
|---|---|---|
| CFU-E | 2 | None |
| Mature BFU-E | 13 | None |
| Primitive BFU-E | 2 | 21 |
| CFU-GM | 73 | 2 |
| CFU-GM large | None | 19 |
| CFU-GEMM | 10 | 5 |
| CFU-GEMM large | None | 49 |
| Blastlike colonies | None | 4 |
| Total | 100 | 100 |
. | Bone marrow cells, % . | c-Kit+/CD31high/Ly-6C-, % . |
|---|---|---|
| CFU-E | 2 | None |
| Mature BFU-E | 13 | None |
| Primitive BFU-E | 2 | 21 |
| CFU-GM | 73 | 2 |
| CFU-GM large | None | 19 |
| CFU-GEMM | 10 | 5 |
| CFU-GEMM large | None | 49 |
| Blastlike colonies | None | 4 |
| Total | 100 | 100 |
Cells were seeded on methylcellulose and colonies were scored at day 14. Percentages shown are the results of 3 experiments.
CFU-E indicates erythroid colony-forming units; mature BFU-E, progenitors that give rise to colonies constituted by 3 up to 8 erythroblast clusters; primitive BFU-E, progenitors that give rise to 9 or more clusters of hemoglobinized erythroblasts; CFU-GM, granulocyte-macrophage colony-forming unit; and CFU-GEMM, granulocyte-erythrocyte-megakaryocyte-macrophage colony-forming unit.