Risk factors for developing LONIPCs
. | All patients . | . | LONIPC patients . | . | . | ||
---|---|---|---|---|---|---|---|
Factor . | n . | % . | n . | % . | P . | ||
Sex: male vs female | 52 of 76 | 68.4 | 12 of 18 | 66.7 | NS | ||
Source | |||||||
Related PBSCs vs BM | 18 of 27 | 66.7 | 6 of 7 | 85.7 | NS | ||
Unrelated BM vs related BM | 47 of 56 | 83.9 | 11 of 12 | 91.7 | NS | ||
HLA compatibility: mismatch vs full match | 17 of 76 | 22.4 | 4 of 18 | 22.2 | NS | ||
Blood type mismatch: + vs − | 28 of 76 | 36.8 | 5 of 18 | 27.8 | NS | ||
Sex mismatch: + vs − | 29 of 76 | 38.2 | 7 of 18 | 38.9 | NS | ||
Conditioning: TBI/TLI vs non-TBI/TLI | 35 of 76 | 46.1 | 11 of 18 | 61.1 | NS | ||
GVHD prophylaxis: CsA vs FK506 | 60 of 76 | 78.9 | 16 of 18 | 88.9 | NS | ||
Acute GVHD: II-IV vs 0/I | 29 of 76 | 38.2 | 8 of 18 | 44.4 | NS | ||
Chronic GVHD: extensive vs 0/limited | 37 of 76 | 48.7 | 15 of 18 | 83.3 | .0008 | ||
Liver: + vs − | 32 of 76 | 42.1 | 9 of 18 | 50.0 | NS | ||
Skin: + vs − | 35 of 76 | 46.1 | 10 of 18 | 55.6 | NS | ||
Sicca syndrome: + vs − | 33 of 76 | 43.4 | 15 of 18 | 83.3 | <.0001 | ||
Disease status: high vs standard | 38 of 69 | 55.1 | 14 of 17 | 82.4 | .0092 |
. | All patients . | . | LONIPC patients . | . | . | ||
---|---|---|---|---|---|---|---|
Factor . | n . | % . | n . | % . | P . | ||
Sex: male vs female | 52 of 76 | 68.4 | 12 of 18 | 66.7 | NS | ||
Source | |||||||
Related PBSCs vs BM | 18 of 27 | 66.7 | 6 of 7 | 85.7 | NS | ||
Unrelated BM vs related BM | 47 of 56 | 83.9 | 11 of 12 | 91.7 | NS | ||
HLA compatibility: mismatch vs full match | 17 of 76 | 22.4 | 4 of 18 | 22.2 | NS | ||
Blood type mismatch: + vs − | 28 of 76 | 36.8 | 5 of 18 | 27.8 | NS | ||
Sex mismatch: + vs − | 29 of 76 | 38.2 | 7 of 18 | 38.9 | NS | ||
Conditioning: TBI/TLI vs non-TBI/TLI | 35 of 76 | 46.1 | 11 of 18 | 61.1 | NS | ||
GVHD prophylaxis: CsA vs FK506 | 60 of 76 | 78.9 | 16 of 18 | 88.9 | NS | ||
Acute GVHD: II-IV vs 0/I | 29 of 76 | 38.2 | 8 of 18 | 44.4 | NS | ||
Chronic GVHD: extensive vs 0/limited | 37 of 76 | 48.7 | 15 of 18 | 83.3 | .0008 | ||
Liver: + vs − | 32 of 76 | 42.1 | 9 of 18 | 50.0 | NS | ||
Skin: + vs − | 35 of 76 | 46.1 | 10 of 18 | 55.6 | NS | ||
Sicca syndrome: + vs − | 33 of 76 | 43.4 | 15 of 18 | 83.3 | <.0001 | ||
Disease status: high vs standard | 38 of 69 | 55.1 | 14 of 17 | 82.4 | .0092 |
NS indicates not significant.