Table 4.

Cox analysis of variables found to be significant by log-rank analysis


Variable

Values

Hazard ratio

95% CI

P
Event-free survival     
    Trisomy 18   0 = no; 1 = yes   0.51   0.38-0.70   < .001  
    Sex   0 = male; 1 = female   1.81   1.30-2.53   < .001  
    Age   0 = 1-9 y; 1 = 10-16 y   2.06   1.34-3.18   .001  
    Trisomy 10*  0 = no; 1 = yes   NA   NA   > .01  
    Modal number*  0 = 51-53; 1 = 54-65   NA   NA   > .01  
Overall survival     
    Age, y   0 = 1-9 y; 1 = 10-16 y   4.01   2.28-7.04   < .001  
    Trisomy 4   0 = no; 1 = yes   0.43   0.26-0.69   .001  
    Trisomy 18   0 = no; 1 = yes   0.44   0.27-0.72   .001  
    Modal number*
 
0 = 51-53; 1 = 54-65
 
NA
 
NA
 
> .01
 

Variable

Values

Hazard ratio

95% CI

P
Event-free survival     
    Trisomy 18   0 = no; 1 = yes   0.51   0.38-0.70   < .001  
    Sex   0 = male; 1 = female   1.81   1.30-2.53   < .001  
    Age   0 = 1-9 y; 1 = 10-16 y   2.06   1.34-3.18   .001  
    Trisomy 10*  0 = no; 1 = yes   NA   NA   > .01  
    Modal number*  0 = 51-53; 1 = 54-65   NA   NA   > .01  
Overall survival     
    Age, y   0 = 1-9 y; 1 = 10-16 y   4.01   2.28-7.04   < .001  
    Trisomy 4   0 = no; 1 = yes   0.43   0.26-0.69   .001  
    Trisomy 18   0 = no; 1 = yes   0.44   0.27-0.72   .001  
    Modal number*
 
0 = 51-53; 1 = 54-65
 
NA
 
NA
 
> .01
 

CI indicates confidence interval; NA, not applicable.

*

These variables were removed from the model; therefore, hazard ratios and CIs were not determined for them in the final model.

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