Log-rank analysis comparing event-free and overall survival of 700 patients with high-hyperdiploid ALL by age, sex, and white blood cell count
. | . | Event-free survival . | . | . | Overall survival . | . | . | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Group . | No. (%) . | No. of events (%) . | O/E . | P . | No. of deaths (%) . | O/E . | P . | ||||
| Total | 700 (100) | 173 (25) | NA | NA | 68 (10) | NA | NA | ||||
| Sex | .0001 | .08 | |||||||||
| Female | 299 (100) | 49 (16) | 0.66 | 21 (7) | 0.75 | ||||||
| Male | 401 (100) | 124 (31) | 1.25 | 47 (12) | 1.18 | ||||||
| Age, y | .0013 | < .0001 | |||||||||
| 1-9 | 636 (100) | 149 (23) | 0.93 | 52 (8) | 0.83 | ||||||
| 10-16 | 64 (100) | 24 (38) | 1.86 | 16 (25) | 3.13 | ||||||
| WBC count, × 109/L | .94 | .73 | |||||||||
| 0-9 | 389 (100) | 92 (24) | 0.93 | 39 (10) | 1.02 | ||||||
| 10-19 | 118 (100) | 28 (24) | 0.95 | 9 (8) | 0.79 | ||||||
| 20-49 | 117 (100) | 37 (32) | 1.42 | 12 (10) | 1.07 | ||||||
| 50-99 | 52 (100) | 11 (21) | 0.87 | 5 (10) | 1.01 | ||||||
| 100+ | 24 (100) | 5 (21) | 0.83 | 3 (13) | 1.29 | ||||||
. | . | Event-free survival . | . | . | Overall survival . | . | . | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Group . | No. (%) . | No. of events (%) . | O/E . | P . | No. of deaths (%) . | O/E . | P . | ||||
| Total | 700 (100) | 173 (25) | NA | NA | 68 (10) | NA | NA | ||||
| Sex | .0001 | .08 | |||||||||
| Female | 299 (100) | 49 (16) | 0.66 | 21 (7) | 0.75 | ||||||
| Male | 401 (100) | 124 (31) | 1.25 | 47 (12) | 1.18 | ||||||
| Age, y | .0013 | < .0001 | |||||||||
| 1-9 | 636 (100) | 149 (23) | 0.93 | 52 (8) | 0.83 | ||||||
| 10-16 | 64 (100) | 24 (38) | 1.86 | 16 (25) | 3.13 | ||||||
| WBC count, × 109/L | .94 | .73 | |||||||||
| 0-9 | 389 (100) | 92 (24) | 0.93 | 39 (10) | 1.02 | ||||||
| 10-19 | 118 (100) | 28 (24) | 0.95 | 9 (8) | 0.79 | ||||||
| 20-49 | 117 (100) | 37 (32) | 1.42 | 12 (10) | 1.07 | ||||||
| 50-99 | 52 (100) | 11 (21) | 0.87 | 5 (10) | 1.01 | ||||||
| 100+ | 24 (100) | 5 (21) | 0.83 | 3 (13) | 1.29 | ||||||
O/E indicates observed versus expected ratio; NA, not applicable.