Table 1.

Clinical and pathological features of MLBCL and DLBCL patients and tumors


Clinical feature

MLBCL, n = 34

DLBCL, n = 176
Median age, y (range)   32 (14-59)   64 (20-92)  
Sex (%)   
   Female   24 (71)   84 (48)  
   Male   10 (29)   92 (52)  
Stage (%)   
   I/II   25 (74)   53 (30)  
   III/IV   9 (26)   115 (65)  
   Unknown   0 (0)   8 (5)  
Pathology (%)   N/A  
   Sclerosis    
      Present   32 (94)   
      Absent   2 (6)   
   Immunoglobulin by IHC*   
      Present   3 (12)   
      Absent   20 (77)   
      Equivocal   3 (12)   
      Not available   8   
FISH   N/A 
   BCL2 rearrangements   0   
   BCL6 rearrangements
 
1
 

 

Clinical feature

MLBCL, n = 34

DLBCL, n = 176
Median age, y (range)   32 (14-59)   64 (20-92)  
Sex (%)   
   Female   24 (71)   84 (48)  
   Male   10 (29)   92 (52)  
Stage (%)   
   I/II   25 (74)   53 (30)  
   III/IV   9 (26)   115 (65)  
   Unknown   0 (0)   8 (5)  
Pathology (%)   N/A  
   Sclerosis    
      Present   32 (94)   
      Absent   2 (6)   
   Immunoglobulin by IHC*   
      Present   3 (12)   
      Absent   20 (77)   
      Equivocal   3 (12)   
      Not available   8   
FISH   N/A 
   BCL2 rearrangements   0   
   BCL6 rearrangements
 
1
 

 

N/A indicates not available.

*

MLBCL immunoglobulin status by immunohistochemistry (IHC) available for 26 patients (% positive calculated on available cases)

MLBCL interphase FISH available: BCL2, 17 patients; BCL6, 19 patients

To be described in a subsequent analysis

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