Multivariable analysis of factors affecting CD4+ Th response (assessed by LPR) and CD8+ CTL function at 3 months after transplantation
. | CD4+ Th function . | . | . | CD8+ CTL function . | . | . | ||||
---|---|---|---|---|---|---|---|---|---|---|
Factor . | RR . | 95% CI . | P . | RR . | 95% CI . | P . | ||||
Steroid use, greater than 1 mg/kg/d | 0.01 | < 0.001-0.05 | < .0001 | < 0.001 | < 0.001-0.49 | .01 | ||||
Peripheral blood source of stem cells | — | NS | — | 8.10 | 1.17-164.82 | .03 | ||||
CD4 count less than 100/mm3 | 0.29 | 0.10-0.80 | .02 | — | NA | — | ||||
CD8 count less than 50/mm3 | — | NA | — | < 0.001 | < 0.001-0.93 | .04 |
. | CD4+ Th function . | . | . | CD8+ CTL function . | . | . | ||||
---|---|---|---|---|---|---|---|---|---|---|
Factor . | RR . | 95% CI . | P . | RR . | 95% CI . | P . | ||||
Steroid use, greater than 1 mg/kg/d | 0.01 | < 0.001-0.05 | < .0001 | < 0.001 | < 0.001-0.49 | .01 | ||||
Peripheral blood source of stem cells | — | NS | — | 8.10 | 1.17-164.82 | .03 | ||||
CD4 count less than 100/mm3 | 0.29 | 0.10-0.80 | .02 | — | NA | — | ||||
CD8 count less than 50/mm3 | — | NA | — | < 0.001 | < 0.001-0.93 | .04 |
Units per mm3 equal × 109/L. RR indicates relative risk; —, value not provided; NS, not significant; and NA, not applicable.