Table 3. Gains and parental origin of... | American Society of Hematology

Table 3.

Gains and parental origin of duplicated chromosomes in 10 hyperdiploid childhood pre-B ALL

	Chromosome
Patient	2	4	5	6	7	8	9	10	11	12	13	14	15	17	18	21	22	X
1	NI	M	D	P	D	D	D	M	D	NI	D	M	D	M	P	T	D	P/pat
2	D	D	D	M	D	D	D	P	D	NI	D	M	NI	M	D/mut	T	D	—
3	D	P/mut	D	P	D	D	D	D	D	D	D	P	D	M	M	T	D	D/NI
4	D	M	D	P	D	P	D	P	D	D	D	M	D	P	M	T	D	P/mat
5	LOH	M	D	M	D	D/mut	D	P	D	LOH	NI	M	D	M	P	T	D	—
6	NI	M	D	P	NI	D	P	P	D	NI	D	D	D	M	D	T	D	—
7	NI	P	D	D	NI	D	D	D	D	D	D	M	NI	P	P	M	D	D/mat
8	D	P	D	M	D	P	LOH/d	D	D	D	D	M	D	P	P	P	D	—
9	NI	M	D	M	D	P	M	M	LOH	D	D	M	D	P	P	T	D	—
10	NI	P	D	M	D	P	LOH	P	D	D	D	D	MSI	M	D	T	D	—
P	—	1	—	1	—	.125	—	.453	—	—	—	.0703	—	.754	.453	—	—	.500

	Chromosome
Patient	2	4	5	6	7	8	9	10	11	12	13	14	15	17	18	21	22	X
1	NI	M	D	P	D	D	D	M	D	NI	D	M	D	M	P	T	D	P/pat
2	D	D	D	M	D	D	D	P	D	NI	D	M	NI	M	D/mut	T	D	—
3	D	P/mut	D	P	D	D	D	D	D	D	D	P	D	M	M	T	D	D/NI
4	D	M	D	P	D	P	D	P	D	D	D	M	D	P	M	T	D	P/mat
5	LOH	M	D	M	D	D/mut	D	P	D	LOH	NI	M	D	M	P	T	D	—
6	NI	M	D	P	NI	D	P	P	D	NI	D	D	D	M	D	T	D	—
7	NI	P	D	D	NI	D	D	D	D	D	D	M	NI	P	P	M	D	D/mat
8	D	P	D	M	D	P	LOH/d	D	D	D	D	M	D	P	P	P	D	—
9	NI	M	D	M	D	P	M	M	LOH	D	D	M	D	P	P	T	D	—
10	NI	P	D	M	D	P	LOH	P	D	D	D	D	MSI	M	D	T	D	—
P	—	1	—	1	—	.125	—	.453	—	—	—	.0703	—	.754	.453	—	—	.500

NI indicates not informative; M, maternal chromosome duplicated; D, disomic; P, paternal chromosome duplicated; T, tetrasomic; mut, mutation (difference in the length of the microsatellite repeat during transmission from parent to child); pat, paternal X active; mat, maternal X active; d, homozygous deletion; MSI, microsatellite instability; and —, not done.

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