Relative ZAP70 and CD3 expression levels in patients with VH-mutated and VH-unmutated MCL and CLL
. | VH-mutated MCL . | . | VH-unmutated MCL . | . | ||
|---|---|---|---|---|---|---|
. | ZAP70 . | CD3 . | ZAP70 . | CD3 . | ||
| Patients with MCL | ||||||
| 1 | 0.17 | 0.03 | 0.72 | 1.67 | ||
| 2 | 2.89 | 4.17 | 1.52 | 1.09 | ||
| 3 | 16.48 | 0.51 | 7.30 | 5.08 | ||
| 4 | 7.99 | 7.11 | 0.53 | 0.02 | ||
| 5 | 0.25 | 0.22 | 0.60 | 0.01 | ||
| 6 | 0.30 | 1.43 | 1.48 | 0.12 | ||
| 7 | 0.16 | 0.41 | 2.17 | 0.58 | ||
| 8 | 1.12 | 0.02 | 0.02 | 0.15 | ||
| 9 | 0.04 | 0.29 | 0.03 | 0.06 | ||
| 10 | 0.17 | 4.84 | 0.07 | 0.27 | ||
| 11 | 0.01 | 0.25 | 0.00 | 0.04 | ||
| Median | 0.25 | 0.41 | 0.6 | 0.15 | ||
| Quartiles | 0.165-2.00 | 0.235-2.80 | 0.05-1.50 | 0.05-0.835 | ||
| Patients with CLL | ||||||
| 1 | 1.93 | 3.02 | 4.45 | 0.38 | ||
| 2 | 0.31 | 2.54 | 11.42 | 1.07 | ||
| 3 | 2.09 | 1.80 | 11.05 | 0.29 | ||
. | VH-mutated MCL . | . | VH-unmutated MCL . | . | ||
|---|---|---|---|---|---|---|
. | ZAP70 . | CD3 . | ZAP70 . | CD3 . | ||
| Patients with MCL | ||||||
| 1 | 0.17 | 0.03 | 0.72 | 1.67 | ||
| 2 | 2.89 | 4.17 | 1.52 | 1.09 | ||
| 3 | 16.48 | 0.51 | 7.30 | 5.08 | ||
| 4 | 7.99 | 7.11 | 0.53 | 0.02 | ||
| 5 | 0.25 | 0.22 | 0.60 | 0.01 | ||
| 6 | 0.30 | 1.43 | 1.48 | 0.12 | ||
| 7 | 0.16 | 0.41 | 2.17 | 0.58 | ||
| 8 | 1.12 | 0.02 | 0.02 | 0.15 | ||
| 9 | 0.04 | 0.29 | 0.03 | 0.06 | ||
| 10 | 0.17 | 4.84 | 0.07 | 0.27 | ||
| 11 | 0.01 | 0.25 | 0.00 | 0.04 | ||
| Median | 0.25 | 0.41 | 0.6 | 0.15 | ||
| Quartiles | 0.165-2.00 | 0.235-2.80 | 0.05-1.50 | 0.05-0.835 | ||
| Patients with CLL | ||||||
| 1 | 1.93 | 3.02 | 4.45 | 0.38 | ||
| 2 | 0.31 | 2.54 | 11.42 | 1.07 | ||
| 3 | 2.09 | 1.80 | 11.05 | 0.29 | ||
Relative expression of ZAP70 and CD3 in patients with VH-mutated and -unmutated (n = 22) MCL. For comparison, data from patients with VH-mutated and -unmutated (n = 6) CLL are shown. ZAP70 expression levels are presented as relative expression levels after normalization on the endogenous control gene PGK.