Table 1.

Change in %F-cells and HbF as a percentage of total hemoglobin (%HbF) with treatment


Patients

Pretreatment %F-cells

Maximum %F-cells

P

Pretreatment %HbF

Maximum %HbF

P
HU nonresponders   16.2 ± 10.8   55.1 ± 11.1   .002   2.4 ± 1.6   14.5 ± 2.2   .0006  
HU responders   51.3 ± 6.3   81.2 ± 4.4   .0001   9.0 ± 2.5   23.9 ± 3.1   < .0001  
All patients
 
38.1 ± 7.6
 
71.4 ± 6.5
 
< .0001
 
6.5 ± 1.4
 
20.4 ± 2.0
 
< .0001
 

Patients

Pretreatment %F-cells

Maximum %F-cells

P

Pretreatment %HbF

Maximum %HbF

P
HU nonresponders   16.2 ± 10.8   55.1 ± 11.1   .002   2.4 ± 1.6   14.5 ± 2.2   .0006  
HU responders   51.3 ± 6.3   81.2 ± 4.4   .0001   9.0 ± 2.5   23.9 ± 3.1   < .0001  
All patients
 
38.1 ± 7.6
 
71.4 ± 6.5
 
< .0001
 
6.5 ± 1.4
 
20.4 ± 2.0
 
< .0001
 

Values are mean ± SD. P values determined by 2-tailed paired t test.

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