Multivariable regression models for overall mortality
. | Hazard ratio . | 95% Cl . | P . |
|---|---|---|---|
| Model 1 | |||
| Conditioning regimen | |||
| Other regimens | 1 | — | — |
| Targeted BUCY | 0.3 | 0.1-0.8 | .01 |
| Dupriez classification | |||
| 1 | 1 | — | — |
| 2 | 2.3 | 0.7-8.1 | .19 |
| 3 | 7.2 | 2.1-25.0 | .002 |
| Model 2 | |||
| Platelet count | |||
| × 109/L or higher | 1 | — | — |
| Less than × 109/L | 2.2 | 0.8-6.0 | .13 |
| Dupriez classification | |||
| 1 | 1 | — | — |
| 2 | 2.6 | 0.8-9.1 | .13 |
| 3 | 4.5 | 1.2-16.9 | .03 |
| Model 3 | |||
| Degree of fibrosis | |||
| 1 | 1 | — | — |
| 2 | 3.2 | 0.9-11.4 | .08 |
| 3 | 2.8 | 0.8-9.4 | .11 |
| Dupriez classification | |||
| 1 | 1 | — | — |
| 2 | 2.6 | 0.8-9.3 | .13 |
| 3 | 6.5 | 1.8-22.9 | .004 |
| Model 4 | |||
| Karyotype | |||
| Normal | 1 | — | — |
| Clonal | 5.3 | 1.5-18.2 | .009 |
| Dupriez | |||
| 1 | 1 | — | — |
| 2 | 0.8 | 0.2-3.6 | .82 |
| 3 | 3.4 | 0.9-12.3 | .06 |
. | Hazard ratio . | 95% Cl . | P . |
|---|---|---|---|
| Model 1 | |||
| Conditioning regimen | |||
| Other regimens | 1 | — | — |
| Targeted BUCY | 0.3 | 0.1-0.8 | .01 |
| Dupriez classification | |||
| 1 | 1 | — | — |
| 2 | 2.3 | 0.7-8.1 | .19 |
| 3 | 7.2 | 2.1-25.0 | .002 |
| Model 2 | |||
| Platelet count | |||
| × 109/L or higher | 1 | — | — |
| Less than × 109/L | 2.2 | 0.8-6.0 | .13 |
| Dupriez classification | |||
| 1 | 1 | — | — |
| 2 | 2.6 | 0.8-9.1 | .13 |
| 3 | 4.5 | 1.2-16.9 | .03 |
| Model 3 | |||
| Degree of fibrosis | |||
| 1 | 1 | — | — |
| 2 | 3.2 | 0.9-11.4 | .08 |
| 3 | 2.8 | 0.8-9.4 | .11 |
| Dupriez classification | |||
| 1 | 1 | — | — |
| 2 | 2.6 | 0.8-9.3 | .13 |
| 3 | 6.5 | 1.8-22.9 | .004 |
| Model 4 | |||
| Karyotype | |||
| Normal | 1 | — | — |
| Clonal | 5.3 | 1.5-18.2 | .009 |
| Dupriez | |||
| 1 | 1 | — | — |
| 2 | 0.8 | 0.2-3.6 | .82 |
| 3 | 3.4 | 0.9-12.3 | .06 |
Additional models considered were as follows: conditioning regimen and fibrosis; conditioning regimen and platelet count; platelet count and fibrosis; conditioning regimen and age; Dupriez classification and age; fibrosis and age; and platelet count and age. Those models did not appear to contribute substantially to the data shown above.